Adhesions of cells to extracellular matrix and adjacent cells are mediated by integrins and
VE-cadherin, respectively. Although these adhesion processes play crucial roles in vascular …

Endothelial cells lining the inner vascular wall form a monolayer that contributes to the
selective permeability of endothelial barrier. This selective permeability is mainly regulated …

An important function of the endothelium is to regulate the transport of liquid and solutes
across the semi-permeable vascular endothelial barrier. Two cellular pathways have been …

Destabilization of cell-cell contacts involved in the maintenance of endothelial barrier
function can lead to increased endothelial permeability. This increase in endothelial …

In this review, we present a discussion of diabetes and its complications, including the
macrovascular and microvascular effects, with the latter of consequence to the retina. We …

The adherens junction is a multiprotein complex consisting of the transmembrane vascular
endothelial cadherin (VEC) and cytoplasmic catenins (p120, β-catenin, plakoglobin, α …

Endothelial cells (ECs) are critical for angiogenesis and microRNA plays important roles in
this process. In this study, we investigated the function and mechanism of miR-302c in the …

Vascular endothelial-cadherin (VE-cadherin) controls endothelial cell-cell adhesion and
preserves endothelial integrity. In order to maintain endothelial barrier function, VE-cadherin …

Uncontrolled blood glucose in people with diabetes correlates with endothelial cell
dysfunction, which contributes to accelerated atherosclerosis and subsequent myocardial …

It was reported over a decade ago that tissue inhibitor of metalloproteinases-1 (TIMP-1)
suppresses angiogenesis in experimental models but the mechanism is still incompletely …