Evidence suggests that maternal obesity (MO) can aggravate placental function causing
severe pathologies during the perinatal window. However, molecular changes and …

As the first detailed overview of the subject, Tight Junctions brought together diverse
perspectives from leading investigators to provide a multidisciplinary overview of the field …

Aims: Vascular endothelial (VE) cadherin is a cell adhesion molecule localized at
endothelial cell (EC) junctions. As a major component of endothelial adherens junctions, its …

Acute transitions in cytosolic calcium ([Ca2+] i) through store-operated calcium entry
channels catalyze interendothelial cell gap formation that increases permeability. However …

The binding of plasma protein fibrinogen (Fg) to intercellular adhesion molecule-1 (ICAM-1)
on endothelial cells mediates the attachment of leukocytes and platelets that may result in …

The proliferation of most non-transformed cell types requires cell adhesion and cellular
tension as well as exposure to mitogenic growth factors. Integrins and cadherins provide the …

Endothelial cell-selective adhesion molecule (ESAM) is an immunoglobulin-like
transmembrane protein associated with endothelial tight junctions (TJ). Based on a yeast …

Leukocytes cross the endothelial vessel wall in a process called transendothelial migration
(TEM). The purpose of leukocyte TEM is to clear the causing agents of inflammation in …

Homeostasis of the extracellular matrix is a delicate balance between degradation and
remodeling, the balance being maintained by the interaction of activated matrix …

We determined the role of vascular endothelial (VE)-cadherin complex in regulating the
permeability of pulmonary microvessels. Studies were made in mouse lungs perfused with …