Regulation of the inflammatory response of vascular endothelial cells by EPAC1

E Parnell, BO Smith, TM Palmer, A Terrin… - British journal of …, 2012 - Wiley Online Library
Life‐threatening diseases of the cardiovascular system, like atherosclerosis, are
exacerbated by unwanted inflammation within the structures of large blood vessels. This …

Gingipains from Porphyromonas gingivalis W83 Synergistically Disrupt Endothelial Cell Adhesion and Can Induce Caspase-Independent Apoptosis

SM Sheets, J Potempa, J Travis, HM Fletcher… - Infection and …, 2006 - Am Soc Microbiol
We have shown previously that gingipains from Porphyromonas gingivalis W83 can induce
cell detachment, cell adhesion molecule (CAM) cleavage, and apoptosis in endothelial cells; …

Regulation of angiogenesis by the aging suppressor gene klotho

K Fukino, T Suzuki, Y Saito, T Shindo, T Amaki… - Biochemical and …, 2002 - Elsevier
Advanced age is a major risk factor of peripheral artery disease. We examined the effects of
the aging-suppressor gene klotho on angiogenesis in response to ischemia by introducing …

Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis

R Spagnuolo, M Corada, F Orsenigo, L Zanetta… - Blood, 2004 - ashpublications.org
The junctional membrane protein vascular endothelial (VE)–cadherin mediates contact
inhibition of growth and inhibits apoptosis of endothelial cells. In this article we show that VE …

The role of p38 map kinase in tumor necrosis factor-induced redistribution of vascular endothelial cadherin and increased endothelial permeability

FE Nwariaku, J Chang, X Zhu, Z Liu, SL Duffy… - Shock, 2002 - journals.lww.com
The mechanism by which tumor necrosis factor alpha (TNFα) increases endothelial
permeability is unclear. Vascular endothelial (VE) cadherin (cadherin 5) is an important …

Cross talk between focal adhesion kinase and cadherins: role in regulating endothelial barrier function

SK Quadri - Microvascular research, 2012 - Elsevier
A layer of endothelial cells attached to their underlying matrices by complex transmembrane
structures termed focal adhesion (FA) proteins maintains the barrier property of …

NADPH oxidase mediates vascular endothelial cadherin phosphorylation and endothelial dysfunction

FE Nwariaku, Z Liu, X Zhu, D Nahari, C Ingle, RF Wu… - Blood, 2004 - ashpublications.org
Vascular endothelial activation is an early step during leukocyte/endothelial adhesion and
transendothelial leukocyte migration in inflammatory states. Leukocyte transmigration occurs …

[HTML][HTML] The role of vascular actors in two dimensional dialogue of human bone marrow stromal cell and endothelial cell for inducing self-assembled network

H Li, R Daculsi, M Grellier, R Bareille, C Bourget… - PloS one, 2011 - journals.plos.org
Angiogenesis is very important for vascularized tissue engineering. In this study, we found
that a two-dimensional co-culture of human bone marrow stromal cell (HBMSC) and human …

The role of sphingolipids in endothelial barrier function

PL Jernigan, AT Makley, RS Hoehn, MJ Edwards… - Biological …, 2015 - degruyter.com
Sphingolipids are a ubiquitous family of essential lipids with an increasingly understood role
as biologically active mediators in numerous physiologic and pathologic processes. Two …

Distinct patterns of microvascular endothelial cell morphology are determined by extracellular matrix composition

JF Dye, L Lawrence, C Linge, L Leach, JA Firth… - Endothelium, 2004 - Taylor & Francis
Endothelial interactions with the extracellular matrix (ECM) play important roles in
angiogenesis but whether specific ECM signals can determine specific cellular …