Background and purpose New‐onset refractory status epilepticus (NORSE) is a clinical
presentation, neither a specific diagnosis nor a clinical entity. It refers to a patient without …

Introduction Recent studies prompted the identification of neuroinflammation as a potential
target for the treatment of epilepsy, particularly drug-resistant epilepsy, and refractory status …

Status epilepticus (SE) is a medical emergency resulting from the failure of the mechanisms
involved in seizure termination or from the initiation of pathways involved in abnormally …

The molecular mechanisms leading to infantile epileptic spasm syndrome (IESS) remain
obscure. The only common factor seems to be that the spasms are restricted to a limited …

Introduction Despite the existence of over 30 anti-seizure medications (ASM), including 20
over the last 30 years, a third of patients with epilepsy remain refractory to treatment, with no …

Mutations in KCNQ2 encoding for voltage-gated K channel subunits underlying the neuronal
M-current have been associated with infantile-onset epileptic disorders. The clinical …

Epilepsy is the most common childhood neurological disease, and nearly 20% of affected
children develop drug-resistant childhood epilepsy (DRCE). Using single-cell analysis …

Epilepsy is a neurological disorder with a high prevalence worldwide. Several studies
carried out during the last decades indicate that the administration of cannabinoids as well …

A central role for neuroinflammation in epileptogenesis has recently been suggested by
several investigations. This systematic review explores the role of inflammatory mediators in …

Tic disorder (TD) is a common childhood-onset disease associated with abnormal
development of brain networks involved in the motor and sensory processing. The …