Unraveling the enigma of new‐onset refractory status epilepticus: a systematic review of aetiologies
S Lattanzi, M Leitinger, C Rocchi… - European Journal of …, 2022 - Wiley Online Library
Background and purpose New‐onset refractory status epilepticus (NORSE) is a clinical
presentation, neither a specific diagnosis nor a clinical entity. It refers to a patient without …
presentation, neither a specific diagnosis nor a clinical entity. It refers to a patient without …
Targeting inflammatory mediators in epilepsy: a systematic review of its molecular basis and clinical applications
G Costagliola, G Depietri, A Michev, A Riva… - Frontiers in …, 2022 - frontiersin.org
Introduction Recent studies prompted the identification of neuroinflammation as a potential
target for the treatment of epilepsy, particularly drug-resistant epilepsy, and refractory status …
target for the treatment of epilepsy, particularly drug-resistant epilepsy, and refractory status …
Neuroinflammation and status epilepticus: a narrative review unraveling a complex interplay
T Foiadelli, A Santangelo, G Costagliola… - Frontiers in …, 2023 - frontiersin.org
Status epilepticus (SE) is a medical emergency resulting from the failure of the mechanisms
involved in seizure termination or from the initiation of pathways involved in abnormally …
involved in seizure termination or from the initiation of pathways involved in abnormally …
[HTML][HTML] Biochemical mechanisms in pathogenesis of infantile epileptic spasm syndrome
R Riikonen - Seizure, 2023 - Elsevier
The molecular mechanisms leading to infantile epileptic spasm syndrome (IESS) remain
obscure. The only common factor seems to be that the spasms are restricted to a limited …
obscure. The only common factor seems to be that the spasms are restricted to a limited …
Epilepsy: expert opinion on emerging drugs in phase 2/3 clinical trials
AW Pong, J Ross, I Tyrlikova, AJ Giermek… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Despite the existence of over 30 anti-seizure medications (ASM), including 20
over the last 30 years, a third of patients with epilepsy remain refractory to treatment, with no …
over the last 30 years, a third of patients with epilepsy remain refractory to treatment, with no …
Nine patients with KCNQ2-related neonatal seizures and functional studies of two missense variants
S Chokvithaya, N Caengprasath, A Buasong… - Scientific Reports, 2023 - nature.com
Mutations in KCNQ2 encoding for voltage-gated K channel subunits underlying the neuronal
M-current have been associated with infantile-onset epileptic disorders. The clinical …
M-current have been associated with infantile-onset epileptic disorders. The clinical …
Neuro-immune crosstalk in drug-resistant epilepsy
BM Andersen, FJ Quintana - Nature Neuroscience, 2022 - nature.com
Epilepsy is the most common childhood neurological disease, and nearly 20% of affected
children develop drug-resistant childhood epilepsy (DRCE). Using single-cell analysis …
children develop drug-resistant childhood epilepsy (DRCE). Using single-cell analysis …
Targeting endocannabinoid system in epilepsy: for good or for bad
Epilepsy is a neurological disorder with a high prevalence worldwide. Several studies
carried out during the last decades indicate that the administration of cannabinoids as well …
carried out during the last decades indicate that the administration of cannabinoids as well …
A Systematic Review of the Predictive and Diagnostic Uses of Neuroinflammation Biomarkers for Epileptogenesis
MJ Aguilar-Castillo, P Cabezudo-García… - International Journal of …, 2024 - mdpi.com
A central role for neuroinflammation in epileptogenesis has recently been suggested by
several investigations. This systematic review explores the role of inflammatory mediators in …
several investigations. This systematic review explores the role of inflammatory mediators in …
Changes of cytokines in children with tic disorder
Y Tao, P Xu, W Zhu, Z Chen, X Tao, J Liu, Z Xue… - Frontiers in …, 2022 - frontiersin.org
Tic disorder (TD) is a common childhood-onset disease associated with abnormal
development of brain networks involved in the motor and sensory processing. The …
development of brain networks involved in the motor and sensory processing. The …