This paper describes the synthesis and O2 binding properties of core–shell structured
hemoglobin (Hb) nanoparticles (NPs), artificial O2 carriers of five types, as designed for use …

Background Total liquid ventilation (TLV) of the lungs could provide radically new benefits in
critically ill patients requiring lung lavage or ultra-fast cooling after cardiac arrest. It consists …

Precise measurement of dissolved CO 2 gas concentration in perfluorocarbon (PFC)
solution is essential to the implementation and understanding of extra-pulmonary gas …

Timely administration of donor red blood cells (RBCs) is a crucial and life-saving procedure
to restore tissue oxygenation in patients suffering from acute blood loss. However, important …

According to recent reports, the yearly mortality rate is 1.9 million worldwide from
hemorrhage (1). This stunning statistic has been slightly improved from the estimated 5 …

The search for a clinically affordable substitute of human blood for transfusion is still an
unmet need of modern society. More than 50 years of research on acellular hemoglobin …

This article reviews the management of patients requesting or requiring surgery without
transfusion, including patient identification and informed consent, determining preoperative …

Artificial blood for clinical use is not yet available therefore, we previously developed
artificial oxygen carriers (capsules) and showed their functionality in vitro and …

Osteoporosis is a major public health threat with significant physical, psychosocial, and
financial consequences. The calcaneus bone has been used as a measurement site for risk …

This article presents a novel mechatronic setup intended for providing respiratory support to
patients suffering from pulmonary failure. The setup relies upon the circulation of an …