Over 200 interstitial lung diseases, from ultra rare to relatively common, are recognised.
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …

The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

The airway epithelium represents a physical barrier to the external environment acting as
the first line of defence against potentially harmful environmental stimuli including microbes …

Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing lung disease of indeterminate
etiology and limited therapeutic options. The initiation, development, and progression of IPF …

Background Alterations in the respiratory microbiome are common in chronic lung diseases,
correlate with decreased lung function, and have been associated with disease progression …

Culture-independent microbiology has transformed our understanding of the respiratory
microbiome in health and disease (1). Enabled by advances in next-generation sequencing …

Fibrotic Interstitial lung diseases (ILDs) are complex disorders of variable clinical behaviour.
The majority of them cause significant morbidity, whilst Idiopathic Pulmonary Fibrosis (IPF) is …

Rationale: Chronic hypersensitivity pneumonitis (CHP) is a condition that arises after
repeated exposure and sensitization to inhaled antigens. The lung microbiome is …

Importance Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited treatment
options. Patients with IPF have altered lung microbiota, with bacterial burden within the …

Idiopathic pulmonary fibrosis is an etiologically complex interstitial lung disease
characterized by progressive scarring of the lungs with a subsequent decline in lung …