Most types of cells in the body do not express the capability of catabolizing cholesterol, so
cholesterol efflux is essential for homeostasis. For instance, macrophages possess four …

Blood lipoproteins are formed by various amounts of cholesterol (C), triglycerides (TGs),
phospholipids, and apolipoproteins (Apos). ApoA1 is the major structural protein of high …

When nanoparticles (NPs) enter a physiological environment, medium components compete
for binding to the NP surface leading to formation of a rich protein shell known as the …

The past decade has seen a significant increase in interest in the use of polymeric
nanocarriers in medical applications. In particular, when used as drug vectors in targeted …

Epidemiologic studies detected an inverse relationship between HDL (high-density
lipoprotein) cholesterol (HDL-C) levels and atherosclerotic cardiovascular disease …

Cholesterol is an essential component of cell barrier formation and signaling transduction
involved in many essential physiologic processes. For this reason, cholesterol metabolism …

Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

HDLs protect against the development of atherosclerosis, but the underlying mechanisms
are poorly understood. HDL and its apolipoproteins can promote cholesterol efflux from …

In the fasted state, induction of hepatic glucose output and fatty acid oxidation is essential to
sustain energetic balance. Production and oxidation of glucose and fatty acids by the liver …

High-density lipoprotein heterogeneity and function in rever... : Current Opinion in Lipidology
High-density lipoprotein heterogeneity and function in reverse cholesterol transport : Current …