Mechanisms and physiological significance of the cholinergic control of pancreatic β-cell function
P Gilon, JC Henquin - Endocrine reviews, 2001 - academic.oup.com
Acetylcholine (ACh), the major parasympathetic neurotransmitter, is released by
intrapancreatic nerve endings during the preabsorptive and absorptive phases of feeding. In …
intrapancreatic nerve endings during the preabsorptive and absorptive phases of feeding. In …
Amylin agonists: a novel approach in the treatment of diabetes
Amylin is a peptide hormone that is cosecreted with insulin from the pancreatic β-cell and is
thus deficient in diabetic people. It inhibits glucagon secretion, delays gastric emptying, and …
thus deficient in diabetic people. It inhibits glucagon secretion, delays gastric emptying, and …
Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis
Summary Melanocortin-4 receptor (MC4R) mutations cause dysregulation of energy
balance and hyperinsulinemia. We have used mouse models to study the physiological …
balance and hyperinsulinemia. We have used mouse models to study the physiological …
Glucagon-like peptide-1 inhibits gastric emptying via vagal afferent-mediated central mechanisms
NI˙ meryüz, BC Yeğen, A Bozkurt… - American Journal …, 1997 - journals.physiology.org
Exogenous administration of glucagon-like peptide-1-(7—36) amide (GLP-1), an
insulinotropic hormone, inhibits gastric emptying and acid secretion in humans. The role of …
insulinotropic hormone, inhibits gastric emptying and acid secretion in humans. The role of …
Characterization of the effects of pancreatic polypeptide in the regulation of energy balance
A Asakawa, A Inui, H Yuzuriha, N Ueno, G Katsuura… - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: Pancreatic polypeptide (PP) belongs to a family of peptides
including neuropeptide Y and peptide YY. We examined the role of PP in the regulation of …
including neuropeptide Y and peptide YY. We examined the role of PP in the regulation of …
Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of …
RM Buijs, SJ Chun, A Niijima… - Journal of …, 2001 - Wiley Online Library
To reveal brain regions and transmitter systems involved in control of pancreatic hormone
secretion, specific vagal and sympathetic denervation were combined with injection of a …
secretion, specific vagal and sympathetic denervation were combined with injection of a …
Autonomic neural regulation of immunity
The 'cytokine theory of disease'states that an overproduction of cytokines can cause the
clinical manifestations of disease. Much effort has been expended to determine how …
clinical manifestations of disease. Much effort has been expended to determine how …
Glial functions in the blood-brain communication at the circumventricular organs
S Miyata - Frontiers in Neuroscience, 2022 - frontiersin.org
The circumventricular organs (CVOs) are located around the brain ventricles, lack a blood-
brain barrier (BBB) and sense blood-derived molecules. This review discusses recent …
brain barrier (BBB) and sense blood-derived molecules. This review discusses recent …
Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor
Second generation antipsychotics (SGAs) are widely prescribed to treat various disorders,
most notably schizophrenia and bipolar disorder; however, SGAs can cause abnormal …
most notably schizophrenia and bipolar disorder; however, SGAs can cause abnormal …
Bioelectronic medicine: from preclinical studies on the inflammatory reflex to new approaches in disease diagnosis and treatment
Bioelectronic medicine is an evolving field in which new insights into the regulatory role of
the nervous system and new developments in bioelectronic technology result in novel …
the nervous system and new developments in bioelectronic technology result in novel …