Dipeptidyl peptidase 3 (DPP3), a zinc‐dependent aminopeptidase, is a highly conserved
enzyme among higher animals. The enzyme cleaves dipeptides from the N‐terminus of tetra …

Dipeptidyl peptidase III (DPP III) was originally thought to be a housekeeping enzyme that
contributes to intracellular peptide catabolism. More specific roles for this cytosolic …

Objectives Thromboinflammation, resulting from a complex interaction between
thrombocytopathy, coagulopathy, and endotheliopathy, contributes to increased mortality in …

Purpose: Adrecizumab, a non-neutralizing antibody of adrenomedullin (ADM) was recently
investigated regarding its potential to restore endothelial barrier function in septic shock …

Sepsis is a life-threatening state that arises due to a hyperactive inflammatory response
stimulated by infection and rarely other insults (eg, non-infections tissue injury). Although …

Introduction Dipeptidyl peptidase-3 (DPP3) is a protease involved in the degradation of
several cardiovascular mediators. Adrenomedullin (bio-ADM) is a peptide essential for …

The coronavirus disease 2019 (COVID-19) pandemic has placed a significant burden on
hospitals worldwide. Objective biomarkers for early risk stratification and clinical …

Abstract Background and Aims Dipeptidyl peptidase 3 (DPP3) is a protease involved in the
degradation of angiotensin II which disturbs peripheral blood pressure regulation and …

Fabry disease (FD) is caused by α-galactosidase A (AGAL) enzyme deficiency, leading to
globotriaosylceramide accumulation (Gb3) in several cell types. Pain is one of the …

Cardiovascular disease is the leading cause of death globally among non-communicable
diseases, which imposes a serious socioeconomic burden on patients and the healthcare …