Background: Breast cancer is the second leading cause of cancer-related death among
women worldwide. Previous studies have suggested that propofol plays key roles in cancer …

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related
death worldwide, and often chemotherapy fails due to post-treatment cell survival and …

Phosphorylation of key proteins can have profound effects on normal and diseased protein
interaction networks. Breast tumor kinase (BRK) is a non-receptor protein tyrosine kinase …

Role of c-Cbl in skeletal muscle energy metabolism in relation to obesity Page 1 Role of c-Cbl
in skeletal muscle energy metabolism in relation to obesity A thesis submitted in fulfilment of …

Abstract Transforming Growth Factor beta (TGFβ) is a pivotal cytokine in regulating our
immune responses. TGFβ exerts many effects through T-cells, which are an important cell …

In mammals, Casitas B-lineage lymphoma (Cbl) family proteins (Cbl, Cbl-b and Cbl-c) are
E3 ubiquitin ligases that function as attenuators of tyrosine kinase mediated signal …

The organ-resident stem cells are responsible for development as well as life-long
maintenance of adult organs and tissues. These cells are few in numbers but possess the …

Las células mieloides supresoras (CMS) constituyen una población de células con actividad
regulatoria que controla las respuestas inflamatorias crónicas y promueve el escape …