Inflammation in intracerebral hemorrhage: from mechanisms to clinical translation

Y Zhou, Y Wang, J Wang, RA Stetler, QW Yang - Progress in neurobiology, 2014 - Elsevier
Intracerebral hemorrhage (ICH) accounts for 10–15% of all strokes and is associated with
high mortality and morbidity. Currently, no effective medical treatment is available to improve …

Injury mechanisms in acute intracerebral hemorrhage

DA Wilkinson, AS Pandey, BG Thompson, RF Keep… - …, 2018 - Elsevier
Intracerebral hemorrhage (ICH) is the most common hemorrhagic stroke subtype, and rates
are increasing with an aging population. Despite an increase in research and trials of …

Spontaneous intracerebral hemorrhage

AI Qureshi, S Tuhrim, JP Broderick… - … England Journal of …, 2001 - Mass Medical Soc
Nontraumatic intracerebral hemorrhage is bleeding into the parenchyma of the brain that
may extend into the ventricles and, in rare cases, the subarachnoid space. Each year …

Mechanisms of brain injury after intracerebral haemorrhage

G Xi, RF Keep, JT Hoff - The Lancet Neurology, 2006 - thelancet.com
The past decade has resulted in a rapid increase in knowledge of mechanisms underlying
brain injury induced by intracerebral haemorrhage (ICH). Animal studies have suggested …

Complications of intracerebral haemorrhage

JS Balami, AM Buchan - The Lancet Neurology, 2012 - thelancet.com
Intracerebral haemorrhage (ICH) is the most devastating type of stroke and is a leading
cause of disability and mortality. By contrast with advances in ischaemic stroke treatment …

[HTML][HTML] Brain edema formation and therapy after intracerebral hemorrhage

Y Wan, KG Holste, Y Hua, RF Keep, G Xi - Neurobiology of disease, 2023 - Elsevier
Intracerebral hemorrhage (ICH) accounts for about 10% of all strokes in the United States of
America causing a high degree of disability and mortality. There is initial (primary) brain …

Injectable, Micellar Chitosan Self‐Healing Hydrogel for Asynchronous Dual‐Drug Delivery to Treat Stroke Rats

SH Lin, APH Huang, S Hsu - Advanced Functional Materials, 2023 - Wiley Online Library
Stroke is a common disease with high mortality worldwide. The endogenous neural
regeneration during the intracerebral hemorrhage (ICH) stroke is restricted by the brain …

Mechanism and therapy of brain edema after intracerebral hemorrhage

H Zheng, C Chen, J Zhang, Z Hu - Cerebrovascular diseases, 2016 - karger.com
Background: Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high
mortality and disability rate and accounts for about 10-15% of all strokes. The oppression …

Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema

WA Mould, JR Carhuapoma, J Muschelli, K Lane… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Perihematomal edema (PHE) can worsen outcomes after
intracerebral hemorrhage (ICH). Reports suggest that blood degradation products lead to …

Targeting secondary injury in intracerebral haemorrhage—perihaematomal oedema

S Urday, WT Kimberly, LA Beslow… - Nature Reviews …, 2015 - nature.com
Perihaematomal oedema (PHO) is an important pathophysiological marker of secondary
injury in intracerebral haemorrhage (ICH). In this Review, we describe a novel method to …