Simple Summary Despite recent therapeutic advances against cancer, many patients do not
respond well or respond poorly, to treatment and develop resistance to more than one anti …

The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) are
important components of the tumor microenvironment, which have been reported to localize …

The lack of cancer-associated fibroblasts (CAFs) in patient-derived organoid (PDO) models
is a major limitation as CAFs contribute to tumor progression and drug resistance. In the …

Cancer cells resistance to various therapies remains to be a key challenge nowadays. For a
long time, scientists focused on tumor cells themselves for the mechanisms of acquired drug …

The progression of cancer is associated with alterations in the tumor microenvironment,
including changes in extracellular matrix (ECM) composition, matrix rigidity …

Background Increasing evidence has shown that mesenchymal stem cells (MSCs) yield a
favorable therapeutic benefit for thermal burn skin wounds. Human amniotic MSCs …

Simple Summary Cancer cells rely on the surrounding environment to grow and spread.
This environment contains structural components, secreted factors, immune cells, and other …

Aberrant glycosylation is a universal feature of cancer cells and there is now overwhelming
evidence that glycans can modulate pathways intrinsic to tumour cell biology. Glycans are …

Chemotherapy remains the mainstay of treatment in the majority of solid and haematological
malignancies. Resistance to cytotoxic chemotherapy is a major clinical problem and …