Dysfunction of FadA‐cAMP signalling decreases Aspergillus flavus resistance to antimicrobial natural preservative Perillaldehyde and AFB1 biosynthesis

K Yang, Q Geng, Y Luo, R Xie, T Sun… - Environmental …, 2022 - Wiley Online Library
Aspergillus flavus is an opportunistic fungal pathogen that colonizes agriculture crops with
aflatoxin contamination. We found that Perillaldehyde (PAE) effectively inhibited A. flavus …

New insights into copper homeostasis in filamentous fungi

M Antsotegi-Uskola, A Markina-Iñarrairaegui… - International …, 2020 - Springer
Copper is a metal ion that is required as a micronutrient for growth and proliferation.
However, copper accumulation generates toxicity by multiple mechanisms, potentially …

Copper Utilization, Regulation, and Acquisition by Aspergillus fumigatus

N Raffa, N Osherov, NP Keller - International Journal of Molecular …, 2019 - mdpi.com
Copper is an essential micronutrient for the opportunistic human pathogen, Aspergillus
fumigatus. Maintaining copper homeostasis is critical for survival and pathogenesis. Copper …

Cinnamaldehyde, a Promising Natural Preservative Against Aspergillus flavus

S Qu, K Yang, L Chen, M Liu, Q Geng, X He… - Frontiers in …, 2019 - frontiersin.org
The problem of food spoilage due to Aspergillus flavus (A. flavus) needs to be resolved. In
this study, we found that the minimum inhibitory concentration of cinnamaldehyde (CA) that …

Nitric oxide-mediated regulation of Aspergillus flavus asexual development by targeting TCA cycle and mitochondrial function

K Yang, Y Luo, T Sun, H Qiu, Q Geng, Y Li, M Liu… - Journal of Hazardous …, 2024 - Elsevier
Nitric oxide (NO) is a signaling molecule with diverse roles in various organisms. However,
its role in the opportunistic pathogen Aspergillus flavus remains unclear. This study …

Genomic and phenotypic trait variation of the opportunistic human pathogen Aspergillus flavus and its close relatives

EA Hatmaker, M Rangel-Grimaldo, HA Raja… - Microbiology …, 2022 - Am Soc Microbiol
Fungal diseases affect millions of humans annually, yet fungal pathogens remain
understudied. The mold Aspergillus flavus can cause both aspergillosis and fungal keratitis …

p‐Anisaldehyde suppresses Aspergillus flavus infection and aflatoxin biosynthesis via targeting cell structure and Ap1‐regulatory antioxidant system

T Sun, N Zhang, Y Luo, H Qiu, Q Geng, Y Li… - Food …, 2024 - Wiley Online Library
Aflatoxin, mainly produced by Aspergillus flavus, is one of the most notorious mycotoxin for
its toxicity and carcinogenicity. Despite extensive efforts, effective strategies to control A …

The Development of Aspergillus flavus and Biosynthesis of Aflatoxin B1 are Regulated by the Golgi-Localized Mn2+ Transporter Pmr1

S Qu, SD Chi, ZM He - Journal of Agricultural and Food Chemistry, 2024 - ACS Publications
Microorganisms rely on diverse ion transport and trace elements to sustain growth,
development, and secondary metabolism. Manganese (Mn2+) is essential for various …

Enhanced Hemolytic Activity of Mesophilic Aeromonas salmonicida SRW-OG1 Is Brought about by Elevated Temperatures

Y Chen, J Wang, H Cai, M Lin, Y Zhang, L Huang - Microorganisms, 2022 - mdpi.com
Aeromonas salmonicida is a well-known cold-water pathogenic bacterium. Previously, we
reported the first isolation of pathogenic A. salmonicida from diseased Epinephelus …

Role of mitochondrial farnesyltransferase gene in the prevention of the food spoilage fungi Aspergillus flavus by the antimicrobial natural preservative perillaldehyde

Q Zhuo, C Shi, Q Geng, S Wang, B Wang, N Zhang… - Food …, 2024 - Elsevier
Aspergillus flavus, one of the most widely distributed and abundant genus of Aspergillus
worldwide, poses an evident threat as a source of food contamination in grains and cereals …