Bone tissue renewal can be outlined as a complicated mechanism centered on the
interaction between osteogenic and angiogenic events capable of leading to bone formation …

Nowadays, bone diseases and defects as a result of trauma, cancers, infections and
degenerative and inflammatory conditions are increasing. Consequently, bone repair and …

Chitosan is a deacetylated polysaccharide from chitin, the natural biopolymer primarily
found in shells of marine crustaceans and fungi cell walls. Upon deacetylation, the …

Regenerative medicine has sparked interest in potential strategies for bone repair. Bone
defects are widespread and could be caused by trauma, congenital malformations …

Bone tissue is the structural component of the body, which allows locomotion, protects vital
internal organs, and provides the maintenance of mineral homeostasis. Several bone …

Wnt signaling plays a central regulatory role across a remarkably diverse range of functions
during embryonic development, including those involved in the formation of bone and …

The regeneration of bone fractures, resulting from trauma, osteoporosis or tumors, is a major
problem in our super-aging society. Bone regeneration is one of the main topics of concern …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Abstract Hydroxyapatite (HAp), a well-known biomaterial, has witnessed a remarkable
evolution over the years, transforming from a simple biocompatible substance to an …

Bone fracture healing impairment related to mechanical problems has been largely
corrected by advances in fracture management. Better protocols, more strict controls of time …