Modifications of human carboxylesterase for improved prodrug activation

JM Hatfield, M Wierdl, RM Wadkins… - Expert opinion on drug …, 2008 - Taylor & Francis
Background: Carboxylesterases (CEs) are ubiquitous enzymes responsible for the
hydrolysis of numerous clinically useful drugs. As ester moieties are frequently included in …

Regulatory segments of the human gene for telomerase reverse transcriptase

GB Morin, WH Andrews - US Patent 7,879,609, 2011 - Google Patents
US7879609B2 - Regulatory segments of the human gene for telomerase reverse transcriptase
- Google Patents US7879609B2 - Regulatory segments of the human gene for telomerase …

Telomerase promoters sequences for screening telomerase modulators

GB Morin, S Lichtsteiner, A Vasserot, R Adams… - US Patent …, 2008 - Google Patents
Telomerase reverse transcriptase is part of the telomerase complex responsible for
maintaining telomere length and increasing the replicative capacity of progenitor cells …

[HTML][HTML] Механизмы регуляции апоптоза и антиапоптическое действие онкогенных вирусов

АА Фильченков, ЗА Бутенко - Биополимеры и клетка, 2000 - Google 学术搜索
Механизмы регуляции апоптоза и антиапоптическое действие онкогенных вирусов
Page 11 Page 1 ISSN 0233-7657. Биополимеры и клетка. 2000. Т. 16. № 6 Механизмы …

Einfluss molekularbiologischer Verfahren auf nuklearmedizinische Methoden

U Haberkorn - Der Nuklearmediziner, 2005 - thieme-connect.com
Zusammenfassung Die Ergebnisse der Grundlagenforschung liefern Informationen über
viele neue molekulare Strukturen, die als potenzielle neue diagnostische oder …

Magnetic resonance imaging in mouse cancer models

M Muruganandham, JA Koutcher - … , NJ: John Wiley & Sons, Inc, 2004 - books.google.com
Currently MRI is the imaging modality of choice for a wide variety of medical diagnostic
questions and has an important role in the study of small-animal tumor physiology. We …

Assessment of Gene Transfer: Magnetic Resonance Imaging and Nuclear Medicine Techniques

A Altmann, U Haberkorn - … Methods and Overviews, Lung Carcinoma and …, 2008 - Springer
With regard to the clinical application of the gene therapeutic approaches, a tight control of
both the spatial and temporal expression of the therapeutic transgene is required, and …

Механізми регуляції апоптозу і антиапоптична дія онкогенних вірусів

ОО Фільченков, ЗА Бутенко - Biopolymers and Cell, 2000 - biopolymers.org.ua
В огляді проаналізовано молекулярні механізми індукції та блокування апоптозу.
Обговорюються різні антиапоптичні ефекти онкогенних вірусів, що забезпечує …

Imaging Techniques for Gene Therapy: SPECT, PET, and MRI

U Haberkorn, A Altmann - Journal of Pharmacy Practice, 2001 - journals.sagepub.com
Gene therapy by the transfer and expression of suicide genes is performed using genes
coding for nonmammalian enzymes that transform nontoxic prodrugs into toxic metabolites …