Hepatic macrophages play a central role in maintaining homeostasis in the liver, as well as
in the initiation and progression of liver diseases. Hepatic macrophages are mainly derived …

Ample evidence suggests that hepatic macrophages play key roles in the injury and repair
mechanisms during liver disease progression. There are two major populations of hepatic …

A great effort of research has been devoted in the last few years to developing new anti-HBV
therapies of finite duration that also provide effective sustained control of virus replication …

The liver is an essential immunological organ due to its gatekeeper position to bypassing
antigens from the intestinal blood flow and microbial products from the intestinal …

The liver plays a central role in metabolism, protein synthesis and detoxification. It
possesses unique regenerative capacity upon injury. While many factors regulating cellular …

Macrophages, as central components of innate immunity, feature significant heterogeneity.
Numerus studies have revealed the pivotal roles of macrophages in the pathogenesis of …

Acute liver failure (ALF) is a severe liver disease caused by disruptions in the body's
immune microenvironment. In the early stages of ALF, Kupffer cells (KCs) become depleted …

Triclocarban (TCC), an emerging organic contaminant, poses a potential threat to human
health with long-term exposure. Here, Rhodococcus rhodochrous BX2 and Pseudomonas …

Nonalcoholic steatohepatitis (NASH) is becoming common chronic liver disease because of
the increasing global prevalence of obesity and consequently Nonalcoholic fatty liver …

Liver fibrosis is a repair process of chronic liver injuries induced by toxic substances,
pathogens, and inflammation, which exhibits a feature such as deposition of the extracellular …