Malaria represents one of the most serious threats to human health worldwide, and
preventing and curing this parasitic disease still depends predominantly on the …

The malaria parasite Plasmodium spp. varies the expression profile of its genes depending
on the host it resides in and its developmental stage. Virtually all messenger RNA (mRNA) is …

The protein translation machinery of the parasite Plasmodium is the target of important anti-
malarial drugs, and encompasses many promising targets for future drugs. Plasmodium …

The life cycles of apicomplexan parasites such as Plasmodium spp. and Toxoplasma gondii
are complex, consisting of proliferative and latent stages within multiple hosts. Dramatic …

Infection by malaria parasites (Plasmodium spp.) remains one of the leading causes of
morbidity and mortality, especially in tropical regions of the world. Despite the availability of …

Malaria control is threatened by a limited pipeline of effective pharmaceuticals against drug-
resistant strains of Plasmodium falciparum. Components of the mitochondrial electron …

Genetic mapping has been widely employed to search for genes linked to phenotypes/traits
of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice …

Resistance of malaria parasites has quickly developed to almost all used antimalarial drugs.
Accordingly, the discovery of new effective drugs to counter the spread of malaria parasites …

The malaria parasite has been allowed to get perilously close to winning the upper hand in
the race between new drugs and resistance development. Today, just one class of drugs is …

Background and objectives There is a significant interest in identifying clinically effective
drug treatment regimens that minimize the de novo evolution of antimicrobial resistance in …