Although the introduction of universal pertussis immunisation in infants has greatly reduced
the number of reported cases in infants and young children, disease incidence has been …

Age-related changes of the immune system contribute to increased incidence and severity of
infections in the elderly. Vaccination is the most effective measure to prevent infections and …

Preserving good health in old age is of utmost importance to alleviate societal, economic
and health care-related challenges caused by an aging society. The prevalence and …

Besides immunizations against influenza, Streptococcus pneumoniae and herpes zoster,
which are recommended specifically for elderly people, regular booster vaccinations against …

Background. Booster vaccination against tetanus and diphtheria at 10-year intervals is
commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and …

BACKGROUND: Pertussis can cause significant morbidity in elderly patients, who can also
transmit this disease to infants and young children. There is little data available on the use of …

Demographic changes and a more active life-style in older age have contributed to an
increasing public awareness of the need for lifelong vaccination. Currently many older …

Background. We conducted a 5-year follow-up study on the persistence of pertussis-specific
antibody and cell-mediated immunity after booster immunization of adolescents aged 11–13 …

Pertussis is a highly contagious infectious disease caused by Bordetella pertussis that can
be extremely serious, particularly in young infants. For many years the efforts of health …

We have recently demonstrated that single shot vaccinations against tetanus and diphtheria
do not lead to long-lasting immunity against diphtheria in elderly persons despite …