Butyrate and the intestinal epithelium: modulation of proliferation and inflammation in homeostasis and disease

PS Salvi, RA Cowles - Cells, 2021 - mdpi.com
The microbial metabolite butyrate serves as a link between the intestinal microbiome and
epithelium. The monocarboxylate transporters MCT1 and SMCT1 are the predominant …

Gut microbial metabolite butyrate and its therapeutic role in inflammatory bowel disease: a literature review

N Recharla, R Geesala, XZ Shi - Nutrients, 2023 - mdpi.com
Background and objective: Inflammatory bowel disease (IBD), including Crohn's disease
and ulcerative colitis, is a chronic inflammatory disorder characterized by aberrant immune …

Oral exposure to polyethylene microplastics alters gut morphology, immune response, and microbiota composition in mice

M Djouina, C Vignal, A Dehaut, S Caboche, N Hirt… - Environmental …, 2022 - Elsevier
The ubiquitous and growing presence of microplastics (MPs) in all compartments of the
environment raises concerns about their possible harmful effects on human health. Human …

Delivery of short chain fatty acid butyrate to overcome Fusobacterium nucleatum-induced chemoresistance

L Chen, R Zhao, Z Kang, Z Cao, N Liu, J Shen… - Journal of Controlled …, 2023 - Elsevier
The gut microbiota is closely associated with the progression of colorectal cancer (CRC) in
which Fusobacterium nucleatum (F. nucleatum) was found to induce cancer resistance to …

The detrimental effects of micro-and nano-plastics on digestive system: An overview of oxidative stress-related adverse outcome pathway

R Ding, Y Ma, T Li, M Sun, Z Sun, J Duan - Science of The Total …, 2023 - Elsevier
With the massive manufacture and use of plastics, plastic pollution-related environmental
impacts have raised great concern in recent years. As byproducts of plastic fragmentation …

Dysbiotic change in gastric microbiome and its functional implication in gastric carcinogenesis

JY Park, H Seo, CS Kang, TS Shin, JW Kim, JM Park… - Scientific reports, 2022 - nature.com
Although there is a growing interest in the role of gastric microbiome on the development of
gastric cancer, the exact mechanism is largely unknown. We aimed to investigate the …

Rosmarinic acid restores colonic mucus secretion in colitis mice by regulating gut microbiota-derived metabolites and the activation of inflammasomes

Q Wang, K Xu, X Cai, C Wang, Y Cao… - Journal of Agricultural …, 2023 - ACS Publications
Maintaining a steady state of mucus barrier is an important potential target for polyphenol to
exert its anticolitis activity. This study elucidates the pivotal role of polyphenol rosmaric acid …

Curcumin Alleviates DSS‐Induced Anxiety‐Like Behaviors via the Microbial‐Brain‐Gut Axis

F Zhang, Y Zhou, H Chen, H Jiang… - Oxidative medicine …, 2022 - Wiley Online Library
The anxiety and depression caused by inflammatory bowel diseases (IBD) are known to
greatly affect the mental health of patients. The mechanism of psychiatric disorders caused …

Sodium butyrate alleviates intestinal injury and microbial flora disturbance induced by lipopolysaccharides in rats

X Dou, Z Ma, D Yan, N Gao, Z Li, Y Li, X Feng… - Food & Function, 2022 - pubs.rsc.org
Bacterial endotoxin invasion reduces intestinal barrier functions, such as intestinal bacterial
translocation and enteric infection. In this study, we investigated whether sodium butyrate …

Lonicera rupicola Hook. f. et Thoms flavonoids ameliorated dysregulated inflammatory responses, intestinal barrier, and gut microbiome in ulcerative colitis via PI3K …

C Li, L Wang, J Zhao, Y Wei, S Zhai, M Tan, K Guan… - Phytomedicine, 2022 - Elsevier
Abstract Background Lonicera rupicola Hook. f. et Thoms (LRH) is used as a customary
medicinal herb in Tibetans. And LRH flavonoids have excellent anti-inflammatory and …