[HTML][HTML] Mesenchymal stem cell-derived exosomes: applications in regenerative medicine

MD Hade, CN Suire, Z Suo - Cells, 2021 - mdpi.com
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

[HTML][HTML] A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine

S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …

VH298-loaded extracellular vesicles released from gelatin methacryloyl hydrogel facilitate diabetic wound healing by HIF-1α-mediated enhancement of angiogenesis

Y Wang, Z Cao, Q Wei, K Ma, W Hu, Q Huang, J Su… - Acta Biomaterialia, 2022 - Elsevier
Endothelial malfunction is responsible for impaired angiogenesis in diabetic patients,
thereby causing the delayed healing progress of diabetic wounds. Exosomes or …

[HTML][HTML] Effects of mesenchymal stem cell-derived exosomes on autoimmune diseases

Z Shen, W Huang, J Liu, J Tian, S Wang… - Frontiers in …, 2021 - frontiersin.org
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …

Intranasal delivery of mesenchymal stem cell derived exosomes loaded with phosphatase and tensin homolog siRNA repairs complete spinal cord injury

S Guo, N Perets, O Betzer, S Ben-Shaul, A Sheinin… - ACS …, 2019 - ACS Publications
Individuals with spinal cord injury (SCI) usually suffer from permanent neurological deficits,
while spontaneous recovery and therapeutic efficacy are limited. Here, we demonstrate that …

Human umbilical cord blood–derived MSCs exosome attenuate myocardial injury by inhibiting ferroptosis in acute myocardial infarction mice

Y Song, B Wang, X Zhu, J Hu, J Sun, J Xuan… - Cell Biology and …, 2021 - Springer
The exosome of MSCs derived from human umbilical cord blood (HUCB-MSC) has been
reported to have cardioprotective effects on mouse models of acute myocardial infarction …

Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes

Z Xunian, R Kalluri - Cancer Science, 2020 - Wiley Online Library
Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …

[HTML][HTML] Insights into the secretome of mesenchymal stem cells and its potential applications

S Eleuteri, A Fierabracci - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) have regenerative, immunoregulatory properties and can
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …

[HTML][HTML] Hydrogel encapsulation of mesenchymal stem cells and their derived exosomes for tissue engineering

P Khayambashi, J Iyer, S Pillai, A Upadhyay… - International journal of …, 2021 - mdpi.com
Tissue engineering has been an inveterate area in the field of regenerative medicine for
several decades. However, there remains limitations to engineer and regenerate tissues …

Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system

J Zhang, BA Buller, ZG Zhang, Y Zhang, M Lu… - Experimental …, 2022 - Elsevier
Injury of oligodendrocytes (OLs) induces demyelination, and patients with
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …