[HTML][HTML] Mesenchymal stem cell-derived exosomes: applications in regenerative medicine
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …
are then released into the extracellular space through a merging of the multivesicular body …
[HTML][HTML] A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine
S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
VH298-loaded extracellular vesicles released from gelatin methacryloyl hydrogel facilitate diabetic wound healing by HIF-1α-mediated enhancement of angiogenesis
Y Wang, Z Cao, Q Wei, K Ma, W Hu, Q Huang, J Su… - Acta Biomaterialia, 2022 - Elsevier
Endothelial malfunction is responsible for impaired angiogenesis in diabetic patients,
thereby causing the delayed healing progress of diabetic wounds. Exosomes or …
thereby causing the delayed healing progress of diabetic wounds. Exosomes or …
[HTML][HTML] Effects of mesenchymal stem cell-derived exosomes on autoimmune diseases
Z Shen, W Huang, J Liu, J Tian, S Wang… - Frontiers in …, 2021 - frontiersin.org
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …
Intranasal delivery of mesenchymal stem cell derived exosomes loaded with phosphatase and tensin homolog siRNA repairs complete spinal cord injury
Individuals with spinal cord injury (SCI) usually suffer from permanent neurological deficits,
while spontaneous recovery and therapeutic efficacy are limited. Here, we demonstrate that …
while spontaneous recovery and therapeutic efficacy are limited. Here, we demonstrate that …
Human umbilical cord blood–derived MSCs exosome attenuate myocardial injury by inhibiting ferroptosis in acute myocardial infarction mice
Y Song, B Wang, X Zhu, J Hu, J Sun, J Xuan… - Cell Biology and …, 2021 - Springer
The exosome of MSCs derived from human umbilical cord blood (HUCB-MSC) has been
reported to have cardioprotective effects on mouse models of acute myocardial infarction …
reported to have cardioprotective effects on mouse models of acute myocardial infarction …
Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes
Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
[HTML][HTML] Insights into the secretome of mesenchymal stem cells and its potential applications
S Eleuteri, A Fierabracci - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) have regenerative, immunoregulatory properties and can
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …
[HTML][HTML] Hydrogel encapsulation of mesenchymal stem cells and their derived exosomes for tissue engineering
Tissue engineering has been an inveterate area in the field of regenerative medicine for
several decades. However, there remains limitations to engineer and regenerate tissues …
several decades. However, there remains limitations to engineer and regenerate tissues …
Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system
J Zhang, BA Buller, ZG Zhang, Y Zhang, M Lu… - Experimental …, 2022 - Elsevier
Injury of oligodendrocytes (OLs) induces demyelination, and patients with
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …