Cancer is a black spot on the face of humanity in this era of science and technology.
Presently, several classes of anticancer drugs are available in the market, but issues such …

Energetic materials include explosives, propellants, and pyrotechnics that are used for a
variety of military purposes and civilian applications. 1Ā3 An explosive is defined as a …

In this review, we document the most recent developments in azo-linked heteroaromatic
(imidazole, pyrazole, triazole, triazine, tetrazine and oxadiazole) high-nitrogen energetic …

In the current investigation, fifteen novel imidazole-pyridine-based molecules were
synthesized and tested against cell lines of the lung (H1299) and colon (HCT116) …

Dacarbazine is a cell cycle nonspecific antineoplastic alkylating agent used in the treatment
of metastatic malignant melanoma. This chapter contains the descriptions of the drug …

Imidazole and its derivatives are one of the most important and widely used heterocycles in
medicinal chemistry, natural products, and synthetic chemicals. Because of the imidazole …

Many cancers have developed resistance to 5-FU, due to removal by the enzyme uracil-
DNA glycosylase (UDG), a type of base excision repair enzyme (BER) that can excise uracil …

Triazenes are a very useful and diverse class of compounds that have been studied for their
potential in the treatment of many tumors including brain tumor, leukemia and melanoma …

The association of BeX2 (X: H, F, Cl) derivatives with azoles leads to a dramatic increase of
their intrinsic acidity. Hence, whereas 1H‐tetrazole can be considered as a typical N base in …

Cytotoxic drugs constitute an important class of anticancer agents. Over the years, numerous
synthetic cytotoxic compounds have been developed, and many more are in pipeline for …