Autonomic mechanisms are fundamental to human physiological thermoregulation, and
female reproductive hormones have substantial influences on several aspects of these …

Sexually dimorphic effects of alcohol exposure throughout life have been documented in
clinical and preclinical studies. In the past, rates of alcohol use disorder (AUD) were higher …

The GPER1/GPR30 is a membrane estrogen receptor (mER) that binds 17β-estradiol (17β-
E) with high affinity and is thought to play a role in cancer progression and cardiovascular …

Temperature sensitive receptors in the skin and deep body enable the detection of the
external and internal environment, including the perception of thermal stimuli. Changes in …

The neuropeptides tachykinin2 (Tac2) and kisspeptin (Kiss1) in hypothalamic arcuate
nucleus Kiss1 (Kiss1ARH) neurons are essential for pulsatile release of GnRH and …

The estrous cycle is a potent modulator of neuron physiology. In rodents, in vivo ventral
tegmental area (VTA) dopamine (DA) activity has been shown to fluctuate across the estrous …

Metabolic dysfunction underlies several chronic diseases, many of which are exacerbated
by obesity. Dietary interventions can reverse metabolic declines and slow aging, although …

Background Suicide is a leading cause of death, particularly for young adults. Suicidal
behaviours are influenced by a wide-range of personal, social, and cultural factors …

Sexually dimorphic effects of alcohol, following binge drinking, chronic intoxication, and
withdrawal, are documented at the level of the transcriptome and in behavioral and …

Insulin resistance is at the core of the metabolic syndrome, and men exhibit a higher
incidence of metabolic syndrome than women in early adult life, but this sex advantage …