[HTML][HTML] Nutritional immunity: the battle for nutrient metals at the host–pathogen interface

CC Murdoch, EP Skaar - Nature Reviews Microbiology, 2022 - nature.com
Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

[HTML][HTML] The dark side of iron: the relationship between iron, inflammation and gut microbiota in selected diseases associated with iron deficiency anaemia—a …

IJ Malesza, J Bartkowiak-Wieczorek, J Winkler-Galicki… - Nutrients, 2022 - mdpi.com
Iron is an indispensable nutrient for life. A lack of it leads to iron deficiency anaemia (IDA),
which currently affects about 1.2 billion people worldwide. The primary means of IDA …

The human symbiont Bacteroides thetaiotaomicron promotes diet-induced obesity by regulating host lipid metabolism

SH Cho, YJ Cho, JH Park - Journal of Microbiology, 2022 - Springer
The gut microbiome plays an important role in lipid metabolism. Consumption of a high-fat
diet (HFD) alters the bacterial communities in the gut, leading to metabolic disorders …

Why are so many enteric pathogen infections asymptomatic? Pathogen and gut microbiome characteristics associated with diarrhea symptoms and carriage of …

KJ Jesser, G Trueba, KT Konstantinidis, K Levy - Gut Microbes, 2023 - Taylor & Francis
ABSTRACT A high proportion of enteric infections, including those caused by diarrheagenic
Escherichia coli (DEC), are asymptomatic for diarrhea. The factors responsible for the …

[HTML][HTML] Human Pleural Fluid and Human Serum Albumin Modulate the Behavior of a Hypervirulent and Multidrug-Resistant (MDR) Acinetobacter baumannii …

C Pimentel, C Le, MR Tuttobene, T Subils, J Martinez… - Pathogens, 2021 - mdpi.com
Acinetobacter baumannii is a nosocomial pathogen capable of causing serious infections
associated with high rates of morbidity and mortality. Due to its antimicrobial drug resistance …

[HTML][HTML] Development of Novel Antimicrobial and Antiviral Green Synthesized Silver Nanocomposites for the Visual Detection of Fe3+ Ions

A Ali, F Hussain, S Attacha, A Kalsoom, WA Qureshi… - Nanomaterials, 2021 - mdpi.com
In the current research, we present a single-step, one-pot, room temperature green
synthesis approach for the development of functional poly (tannic acid)-based silver …

Trace metal elements: a bridge between host and intestinal microorganisms

Y Ma, Y Fei, S Ding, H Jiang, J Fang, G Liu - Science China Life Sciences, 2023 - Springer
Trace metal elements, such as iron, copper, manganese, and zinc, are essential nutrients for
biological processes. Although their intake demand is low, they play a crucial role in cell …

[HTML][HTML] A detrimental role of NLRP6 in host iron metabolism during Salmonella infection

Q Deng, S Yang, L Sun, K Huang, K Dong, Y Zhu… - Redox biology, 2022 - Elsevier
Maintaining host iron homeostasis is an essential component of nutritional immunity
responsible for sequestrating iron from pathogens and controlling infection. Nucleotide …

[PDF][PDF] Modeling the native ensemble of PhuS using enhanced sampling MD and HDX-ensemble reweighting

KC Kihn, T Wilson, AK Smith, RT Bradshaw… - Biophysical …, 2021 - cell.com
The cytoplasmic heme binding protein from Pseudomonas aeruginosa, PhuS, plays two
essential roles in regulating heme uptake and iron homeostasis. First, PhuS shuttles …

[HTML][HTML] Key players in the regulation of iron homeostasis at the host-pathogen interface

I Ullah, M Lang - Frontiers in Immunology, 2023 - frontiersin.org
Iron plays a crucial role in the biochemistry and development of nearly all living organisms.
Iron starvation of pathogens during infection is a striking feature utilized by a host to quell …