Treatment of HIV-1 with antiretroviral therapy may select mutations in the pol gene
associated with resistance to reverse transcriptase inhibitors and protease inhibitors. To …

Current recommendations indicate the use of HIV-1 drug resistance genotyping in the
treatment of HIV-1 infection, primarily on treatment failure, and in specific instances also …

Background. Technical limitations in the sensitivity of commercial genotyping methods may
prevent clinicians from determining whether drug-resistant human immunodeficiency virus …

HIV-1 drug resistance is caused by mutations in the reverse transcriptase (RT) and protease
enzymes, the molecular targets of antiretroviral therapy. At the beginning of the year 2000 …

Purpose. The effects of pharmacists' interventions on patient outcomes in an HIV primary
care clinic were studied. Methods. All study participants were referred to a pharmacist …

HIV-1 RT and protease sequencing and drug susceptibility testing have been done in
research settings for more than ten years to elucidate the genetic mechanisms of resistance …

The usefulness of rapid pathogen genotyping is widely recognized, but its effective
interpretation and application requires integration into clinical and public health decision …

Background Highly active antiretroviral therapy (HAART) has significantly decreased
mortality among Chinese HIV patients. However, emerging HIV drug resistance (HIVDR) …

To determine the variability of genotypic human immunodeficiency virus (HIV) type 1 drug-
resistance interpretation by available expert systems and its clinical implications, 261 …

ABSTRACT The TRUGENE HIV-1 Genotyping Kit and OpenGene DNA Sequencing System
are designed to sequence the protease (PR)-and reverse transcriptase (RT)-coding regions …