The pros and cons of preimplantation genetic testing for aneuploidy: clinical and laboratory perspectives

Z Rosenwaks, AH Handyside, F Fiorentino… - Fertility and …, 2018 - fertstert.org
Aneuploidy is a major source of adverse outcomes in human reproduction. The impact is so
severe, that the American College of Obstetricians and Gynecologists and the Society for …

Preimplantation genetic testing: single-cell technologies at the forefront of PGT and embryo research

O Tšuiko, EF Gallardo, T Voet, JR Vermeesch - Reproduction, 2020 - rep.bioscientifica.com
While chromosomal mosaicism in the embryo was observed already in the '90s using both
karyotyping and FISH technologies, the full extent of this phenomenon and the overall …

Towards improving embryo prioritization: parallel next generation sequencing of DNA and RNA from a single trophectoderm biopsy

N Fuchs Weizman, BA Wyse, R Antes, Z Ibarrientos… - Scientific reports, 2019 - nature.com
Improved embryo prioritization is crucial in optimizing the results in assisted reproduction,
especially in light of increasing utilization of elective single embryo transfers. Embryo …

New advances in understanding the molecular mechanisms of human embryo implantation in in vitro fertilization programs

AV Charaeva, NP Makarova… - Obstetrics and …, 2023 - journals.eco-vector.com
The data available in the modern scientific literature on the role of the uterine and embryonic
factors in failed euploid embryo implantation were systematically analyzed. The keywords …

Induced pluripotency and intrinsic reprogramming factors: adult stem cells versus somatic cells

SP Shenoy, B Bose, S Kapoor - Molecular Players in iPSC Technology, 2022 - Elsevier
Induced pluripotency has indeed revolutionized the field of pluripotent stem cell biology for
one and a half decades. However, embryonic stem cells (ESCs) have been finding their …

Towards Improving Embryo Selection: Simultaneous Next Generation Sequencing Of DNA And RNA From A Single Trophectoderm Biopsy

NF Weizman, BA Wyse, R Antes, Z Ibarrientos… - bioRxiv, 2018 - biorxiv.org
Improved embryo selection is crucial in optimizing the results from assisted reproduction.
Preimplantation genetic screening reduces time to pregnancy and miscarriages. Correlating …

Biomarkers in Reproductive Medicine: Toward Selecting the Best IVF Embryo for Transfer

D Marin - 2019 - search.proquest.com
Embryonic chromosomal aneuploidies are the major genetic cause of infertility in humans.
As a result, preimplantation genetic diagnosis for aneuploidy (PGT-A) has emerged as a …