α-Granules are essential to normal platelet activity. These unusual secretory granules derive
their cargo from both regulated secretory and endocytotic pathways in megakaryocytes …

The cell wall is essential to nearly every aspect of the biology and pathogenicity of Candida
albicans. Although it was intially considered an almost inert cellular structure that protected …

We analyzed 270 cases of fungal endocarditis (FE) that occurred over 30 years. Vascular
lines, non-cardiac surgery, immunocompromise and injection drug abuse are increasing risk …

Platelets interact with bacterial pathogens through a wide array of cellular and molecular
mechanisms. The consequences of this interaction may significantly influence the balance …

<italic>Candida</italic> Infections: An Overview Page 1 Volume 15, Issue 1 (1987) 1 CANDIDA
INFECTIONS: AN OVERVIEW Author: Frank C. Odds Department of Microbiology University of …

Platelets exhibit archetypal structures and functions enabling their roles as multifunctional
host defense cells. Beyond roles in hemostasis and wound repair, platelets sense and …

The cell surface of Candida albicans is composed of a variety of polysaccharides such as
glucan, chitin, and mannan. The first two components primarily provide structure, while the …

Using a quantitative sonication method, we cultured 1,681 consecutive vascular catheters
submitted to a clinical microbiology laboratory in a 36-month period. A total of 46% of the …

Adhesion and the ability to form filaments are thought to contribute to the pathogenicity of
Candida albicans, the leading cause of fungal disease in immunocompromised patients …

Candida albicans and Staphylococcus aureus form vigorous polymicrobial biofilms in
serum, which may serve as the source of coinfection in patients. More importantly, S. aureus …