Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in
part can become irreversible to conventional therapies, defining the concept of airway …

Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …

Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …

Sex differences in susceptibility, severity, and progression are prevalent for various diseases
in multiple organ systems. This phenomenon is particularly apparent in respiratory diseases …

Pericytes are a heterogeneous population of mesenchymal cells located on the abluminal
surface of microvessels, where they provide structural and biochemical support. Pericytes …

Collagen is the most abundant airway extracellular matrix component and is the primary
determinant of mechanical airway properties. Abnormal airway collagen deposition is …

The different faces of the macrophage in asthma : Current Opinion in Pulmonary Medicine The
different faces of the macrophage in asthma : Current Opinion in Pulmonary Medicine Log in or …

The extracellular matrix (ECM) of the lung plays several important roles in lung function, as it
offers a low resistant pathway that allows the exchange of gases, provides compressive …

Senescent cells can drive age-related tissue dysfunction partially via a senescence-
associated secretory phenotype (SASP) involving proinflammatory and profibrotic factors …