Recent advances in carboxymethyl chitosan-based materials for biomedical applications
Y Geng, H Xue, Z Zhang, AC Panayi, S Knoedler… - Carbohydrate …, 2023 - Elsevier
Chitosan (CS) and its derivatives have been applied extensively in the biomedical field
owing to advantageous characteristics including biodegradability, biocompatibility …
owing to advantageous characteristics including biodegradability, biocompatibility …
Progress in alternative strategies to combat antimicrobial resistance: Focus on antibiotics
Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR),
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials
S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl… - EMBO …, 2023 - embopress.org
Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …
[HTML][HTML] A deep learning approach to antibiotic discovery
Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to
discover new antibiotics. To address this challenge, we trained a deep neural network …
discover new antibiotics. To address this challenge, we trained a deep neural network …
The global preclinical antibacterial pipeline
U Theuretzbacher, K Outterson, A Engel… - Nature Reviews …, 2020 - nature.com
Antibacterial resistance is a great concern and requires global action. A critical question is
whether enough new antibacterial drugs are being discovered and developed. A review of …
whether enough new antibacterial drugs are being discovered and developed. A review of …
Drug combinations: a strategy to extend the life of antibiotics in the 21st century
Antimicrobial resistance threatens a resurgence of life-threatening bacterial infections and
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …
Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi
Terpenoids, critical components of human medicine, are the largest family of natural
products. Fungi are an important source of terpenoids, but many of the corresponding …
products. Fungi are an important source of terpenoids, but many of the corresponding …
Futuristic non-antibiotic therapies to combat antibiotic resistance: A review
The looming problem of resistance to antibiotics in microorganisms is a global health
concern. The drug-resistant microorganisms originating from anthropogenic sources and …
concern. The drug-resistant microorganisms originating from anthropogenic sources and …
Antibiotic discovery: where have we come from, where do we go?
B Ribeiro da Cunha, LP Fonseca, CRC Calado - Antibiotics, 2019 - mdpi.com
Given the increase in antibiotic-resistant bacteria, alongside the alarmingly low rate of newly
approved antibiotics for clinical usage, we are on the verge of not having effective treatments …
approved antibiotics for clinical usage, we are on the verge of not having effective treatments …
Nature is the best source of anticancer drugs: Indexing natural products for their anticancer bioactivity
Cancer is considered one of the primary diseases that cause morbidity and mortality in
millions of people worldwide and due to its prevalence, there is undoubtedly an unmet need …
millions of people worldwide and due to its prevalence, there is undoubtedly an unmet need …