Mitochondrial control of inflammation
Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …
associated molecular patterns (DAMPs) and promote inflammation when released into the …
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
[HTML][HTML] NLRP3 inflammasome activation and cell death
The NLRP3 inflammasome is a cytosolic multiprotein complex composed of the innate
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …
Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury
Y Jiao, T Zhang, C Zhang, H Ji, X Tong, R Xia, W Wang… - Critical Care, 2021 - Springer
Abstract Background Polymorphonuclear neutrophils (PMNs) play an important role in
sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived …
sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived …
[HTML][HTML] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
L Galluzzi, I Vitale, S Warren, S Adjemian… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …
response associated with immunological memory, provided they display sufficient …
The concept of intrinsic versus extrinsic apoptosis
L Lossi - Biochemical Journal, 2022 - portlandpress.com
Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …
FerrDb: a manually curated resource for regulators and markers of ferroptosis and ferroptosis-disease associations
N Zhou, J Bao - Database, 2020 - academic.oup.com
Ferroptosis is a mode of regulated cell death that depends on iron. Cells die from the toxic
accumulation of lipid reactive oxygen species. Ferroptosis is tightly linked to a variety of …
accumulation of lipid reactive oxygen species. Ferroptosis is tightly linked to a variety of …
Roles of RIPK3 in necroptosis, cell signaling, and disease
MJ Morgan, YS Kim - Experimental & molecular medicine, 2022 - nature.com
Abstract Receptor-interacting protein kinase-3 (RIPK3, or RIP3) is an essential protein in the
“programmed” and “regulated” cell death pathway called necroptosis. Necroptosis is …
“programmed” and “regulated” cell death pathway called necroptosis. Necroptosis is …
The ageing brain: molecular and cellular basis of neurodegeneration
Ageing is an inevitable event in the lifecycle of all organisms, characterized by progressive
physiological deterioration and increased vulnerability to death. Ageing has also been …
physiological deterioration and increased vulnerability to death. Ageing has also been …
Cell death in liver diseases: a review
Regulated cell death (RCD) is pivotal in directing the severity and outcome of liver injury.
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …