Update οn the diagnosis and management of systemic lupus erythematosus

A Fanouriakis, N Tziolos, G Bertsias… - Annals of the rheumatic …, 2021 - ard.bmj.com
Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus
erythematosus (SLE). Although SLE is—by and large—a systemic disease, occasionally it …

Treat-to-target in systemic lupus erythematosus: advancing towards its implementation

AR Parra Sánchez, AE Voskuyl… - Nature Reviews …, 2022 - nature.com
The treat-to-target (T2T) concept has improved outcomes for patients with diabetes,
hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well …

EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and …

GC Drosos, D Vedder, E Houben, L Boekel… - Annals of the …, 2022 - ard.bmj.com
Objective To develop recommendations for cardiovascular risk (CVR) management in gout,
vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD) …

Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …

L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …

[HTML][HTML] Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

P Maisonnasse, J Guedj, V Contreras, S Behillil… - Nature, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic and
no antiviral drug or vaccine is yet available for the treatment of this disease,–. Several …

Phase II randomised trial of type I interferon inhibitor anifrolumab in patients with active lupus nephritis

D Jayne, B Rovin, EF Mysler, RA Furie… - Annals of the …, 2022 - ard.bmj.com
Objective To assess the efficacy and safety of the type I interferon receptor antibody,
anifrolumab, in patients with active, biopsy-proven, Class III/IV lupus nephritis. Methods This …

Lupus nephritis: clinical presentations and outcomes in the 21st century

M Gasparotto, M Gatto, V Binda, A Doria… - Rheumatology, 2020 - academic.oup.com
Lupus nephritis (LN) is a frequent and severe manifestation of SLE. Along the decades, the
epidemiology of LN and its clinical presentation have been changing. However, even …

[HTML][HTML] A secondary analysis of the Belimumab International Study in Lupus Nephritis trial examined effects of belimumab on kidney outcomes and preservation of …

BH Rovin, R Furie, YKO Teng, G Contreras, A Malvar… - Kidney international, 2022 - Elsevier
We performed a post hoc analysis of the Belimumab International Study in Lupus Nephritis
(BLISS-LN), a Phase 3, multinational, double-blind, 104-week trial, in which 448 patients …

Hydroxychloroquine in systemic lupus erythematosus: overview of current knowledge

A Dima, C Jurcut, F Chasset… - Therapeutic …, 2022 - journals.sagepub.com
The antimalarial hydroxychloroquine (HCQ) has demonstrated several crucial properties for
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …

Safety and efficacy of long‐term Voclosporin treatment for lupus nephritis in the phase 3 AURORA 2 clinical trial

A Saxena, EM Ginzler, K Gibson… - Arthritis & …, 2023 - Wiley Online Library
Objective AURORA 2 evaluated the long‐term safety, tolerability, and efficacy of voclosporin
compared to placebo in patients with lupus nephritis (LN) receiving an additional two years …