Abstract Prostaglandin E 2 (PGE 2) is a bioactive lipid that elicits a wide range of biological
effects associated with inflammation and cancer. PGE 2 exerts diverse effects on cell …

Cancer cells are highly dependent on different metabolic pathways for sustaining their
survival, growth, and proliferation. Lipid metabolism not only provides the energetic needs of …

Therapeutic resistance has been and remains to be the major challenge in developing
successful treatments for different cancers and therefore, understanding the underlying …

Hepatocellular carcinoma (HCC), a primary liver malignancy, is one of the deadliest cancers
worldwide. Despite orthotopic liver transplantation and hepatic resection representing the …

Epigallocatechingallate (EGCG) is a major bioactive component of green tea and is
associated with health benefits against multiple diseases including cancer. As an indicator …

Receptors are macromolecules that transmit information regulating cell proliferation,
differentiation, migration and apoptosis, play key roles in oncogenic processes and correlate …

We would like to highlight the application of natural products to hepatocellular carcinoma
(HCC). We will focus on the natural products known as flavonoids, which target this disease …

Among a great variety of cell surface receptors, the largest superfamily is G protein-coupled
receptors (GPCRs), also known as seven-transmembrane domain receptors. GPCRs can …

Abstract Epigallocatechin-3-gallate (EGCG) is a natural product with potential anti-cancer
property whose direct target has not been identified. This study intended to investigate …

Numerous studies have documented that in cancer therapy flavonoids extracted from
traditional Chinese medicine have anti-tumor activity or can enhance efficiency of …