Spinal cord stimulation (SCS) is a minimally invasive therapy used for the treatment of
chronic neuropathic pain. SCS is a safe and effective alternative to medications such as …

A systematic literature review and meta-analysis were undertaken to determine if
conditioned pain modulation is dysfunctional in populations with chronic pain. Studies that …

Protocols for testing conditioned pain modulation (CPM) vary between different labs/clinics.
In order to promote research and clinical application of this tool, we summarize the …

Pain diagnosis and management would benefit from the development of objective markers
of nociception and pain. Current research addressing this issue has focused on five main …

Apply the latest scientific and clinical advances with Wall & Melzack's Textbook of Pain, 6th
Edition. Drs. Stephen McMahon, Martin Koltzenburg, Irene Tracey, and Dennis C. Turk …

Objective: The purpose of this narrative review is to analyze the available literature
concerning central sensitization and altered central pain processing in patients with chronic …

Migraine is a cyclic disorder, in which functional and morphological brain changes fluctuate
over time, culminating periodically in an attack. In the migrainous brain, temporal processing …

Several studies in humans and non-human primates have explored and characterised the
features of the cortical representation of the portion of space immediately surrounding the …

Abdominal pain is a common symptom of inflammatory bowel disease (IBD: Crohn's
disease, ulcerative colitis). Pain may arise from different mechanisms, which can include …

Background Many infants admitted to hospital undergo repeated invasive procedures. Oral
sucrose is frequently given to relieve procedural pain in neonates on the basis of its effect on …