Different airway smooth muscle cells phenotypes are involved in intrinsic and extrinsic obstruction in guinea pig asthma model

MD Alvarez-Santos, ÁG Marisol, A González-López… - 2020 - researchsquare.com
Background: Airway obstruction in asthma is driven by airway smooth muscle (ASM)
contraction. Airway obstruction can be induced extrinsically by direct stimulation of ASM with …

SERCA C674 oxidation modulates mitochondrial calcium, indirectly regulating apoptosis in cardiac myocytes

JB Goodman - 2020 - search.proquest.com
Heart failure is a debilitating condition in which the heart cannot meet the metabolic
demands of the body. Chronic β-adrenergic (β-AR) stimulation causes pathological …

[HTML][HTML] INTERRELATIONSHIP OF THE MEDIATOR OF ANGIOGENESIS OF VEGF-A WITH GLUTATHIONE METABOLISM PARAMETERS AND THE CLINICAL …

LA Alexandrova, NA Filippova, A Iman… - The Scientific Notes of …, 2018 - sci-notes.ru
Introduction. In systemic autoimmune diseases with joint damage (SADJD), impaired
angiogenesis occurs, which plays a key role in the progression of proliferative synovitis and …

Role of Toll-like receptor 4 in critical limb ischaemia

AH Navi - 2018 - discovery.ucl.ac.uk
Toll-like receptors (TLR) are key pattern recognition receptors in the innate immune system.
In particular, TLR4-mediated immune response has been implicated in ischaemia-induced …

The role of redox regulation of SERCA in cardiomyocyte hypertrophy

RJ Morgan - 2017 - open.bu.edu
Cardiac hypertrophy is a fundamental response to an increased workload on the heart
characterized by cardiac myocyte (CM) growth and left ventricular (LV) wall thickening. In a …

[PDF][PDF] Роль окислительной модификации белков и их деградации, тиолдисульфидной системы в механизмах дизрегуляции апоптоза при опухолевой …

ОЛ Носарева - 2016 - 83.172.8.139
Актуальность темы исследования. В настоящее время злокачественные
новообразования занимают одну из ведущих позиций среди социально-значимых …

[HTML][HTML] Cardiovascular and Cerebrovascular Aging—New Mechanisms and Insights: Sirtuin 1 ablation in endothelial cells is associated with impaired angiogenesis …

J Maizel, S Xavier, J Chen, CHS Lin… - American Journal of …, 2014 - ncbi.nlm.nih.gov
Discordant myocardial growth and angiogenesis can explain left ventricular (LV)
hypertrophy progressing toward heart failure with aging. Sirtuin 1 expression declines with …

[PDF][PDF] 筋小胞体Ca2+ ATPase2 Cys674Ser knock-in マウスにおける心室性不整脈発生に関する検討

伊藤桂 - 2021 - niad.repo.nii.ac.jp
筋小胞体 Ca2+ ATPase2 Cys674Ser knock-in マウスにおける心室性不整脈発生に関する検討
伊藤 桂 (循 Page 1 筋小胞体 Ca2+ ATPase2 Cys674Ser knock-in マウスにおける心室性不整脈 …

[PDF][PDF] 防衛医科大学校

伊藤桂 - niad.repo.nii.ac.jp
第 2 節 研究プロトコール 7 頁第 3 節 収縮期血圧と脈拍数の測定 7 頁第 4 節 病理組織学的評価
8 頁第 5 節 心筋の 45Ca2+ uptake の評価 8 頁第 6 節 左室収縮能の評価 10 頁第 7 節 …