The Diversity of Escherichia coli Pathotypes and Vaccination Strategies against This Versatile Bacterial Pathogen

P Pokharel, S Dhakal, CM Dozois - Microorganisms, 2023 - mdpi.com
Escherichia coli (E. coli) is a gram-negative bacillus and resident of the normal intestinal
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …

Enteropathogenic Escherichia coli—A Summary of the Literature

AD Mare, CN Ciurea, A Man, B Tudor… - Gastroenterology …, 2021 - mdpi.com
Diarrheal disease is still a major public health concern, as it is still considered an important
cause of death in children under five years of age. A few decades ago, the detection of …

Genome evolution and the emergence of pathogenicity in avian Escherichia coli

L Mageiros, G Méric, SC Bayliss, J Pensar… - Nature …, 2021 - nature.com
Chickens are the most common birds on Earth and colibacillosis is among the most common
diseases affecting them. This major threat to animal welfare and safe sustainable food …

The population genomics of increased virulence and antibiotic resistance in human commensal Escherichia coli over 30 years in France

J Marin, O Clermont, G Royer… - Applied and …, 2022 - Am Soc Microbiol
Escherichia coli is a commensal species of the lower intestine but is also a major pathogen
causing intestinal and extraintestinal infections that is increasingly prevalent and resistant to …

The E phylogroup of Escherichia coli is highly diverse and mimics the whole E. coli species population structure

O Clermont, B Condamine, S Dion… - Environmental …, 2021 - Wiley Online Library
To get a global picture of the population structure of the Escherichia coli phylogroup E,
encompassing the O157: H7 EHEC lineage, we analysed the whole genome of 144 strains …

Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population

F Auvray, A Perrat, Y Arimizu… - Microbial …, 2021 - microbiologyresearch.org
The pks island codes for the enzymes necessary for synthesis of the genotoxin colibactin,
which contributes to the virulence of Escherichia coli strains and is suspected of promoting …

Genomic diversity of non-diarrheagenic fecal Escherichia coli from children in sub-Saharan Africa and south Asia and their relatedness to diarrheagenic E. coli

TH Hazen, JM Michalski, SM Tennant… - Nature …, 2023 - nature.com
Escherichia coli is a frequent member of the healthy human gastrointestinal microbiota, as
well as an important human pathogen. Previous studies have focused on the genomic …

Structural and functional characterization of Stx2k, a new subtype of Shiga toxin 2

AC Hughes, Y Zhang, X Bai, Y Xiong, Y Wang, X Yang… - Microorganisms, 2019 - mdpi.com
Shiga toxin (Stx) is the major virulence factor of Shiga toxin-producing Escherichia coli
(STEC). Stx evolves rapidly and, as such, new subtypes continue to emerge that challenge …

Genomic Epidemiology and Evolution of Escherichia coli in Wild Animals in Mexico

R Murphy, M Palm, V Mustonen, J Warringer… - Msphere, 2021 - Am Soc Microbiol
Escherichia coli is a common bacterial species in the gastrointestinal tracts of warm-blooded
animals and humans. Pathogenicity and antimicrobial resistance in E. coli may emerge via …

Platanus_B: an accurate de novo assembler for bacterial genomes using an iterative error-removal process

R Kajitani, D Yoshimura, Y Ogura, Y Gotoh… - DNA …, 2020 - academic.oup.com
De novo assembly of short DNA reads remains an essential technology, especially for large-
scale projects and high-resolution variant analyses in epidemiology. However, the existing …