Three-dimensional multicellular spheroids (MCSs) have a complex architectural structure,
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …

Background Food-intestine interaction study has always been a hot topic in food science
and nutrition due to diverse physiological functions of intestine. Compared to expensive …

Background In recent years, there has been a surge in the development and application of
single-cell genomics, transcriptomics, proteomics, and metabolomics. The metabolome is …

Despite tremendous advancements in technologies and resources, drug discovery still
remains a tedious and expensive process. Though most cells are cultured using 2D …

Microfluidic technology provides precise, controlled-environment, cost-effective, compact,
integrated, and high-throughput microsystems that are promising substitutes for …

The human gut is important for food digestion and absorption, as well as a venue for a large
number of microorganisms that coexist with the host. Although numerous in vitro models …

Biochemical analysis is crucial in understanding mechanism of life activities and giving
biological insights into life process. With inherent merits in flexible design, microscale of …

Microfluidic technology has become a valuable tool to the scientific community, allowing
researchers to study fine cellular mechanisms with higher variable control compared with …

Localized surface plasmon resonance-based plasmonic biosensors are interesting
candidates for the design of portable optical biosensor platforms owing to their integration …

Microorganisms are not only common pathogens in clinical practice, but also an important
participant in the maintenance of ecological balance, which plays a vital role in food …