Alzheimer's disease and its related dementias in us native americans: A major public health concern

U Sehar, J Kopel, PH Reddy - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) and Alzheimer's related dementias (ADRD) are growing public
health concerns in aged populations of all ethnic and racial groups. AD and ADRD are …

An integrated study on the comprehensive mechanism of Schisandra chinensis polysaccharides mitigating Alzheimer's disease in rats using a UPLC-Q-TOF-MS …

J Fu, J Li, Y Sun, S Liu, F Song, Z Liu - Food & Function, 2023 - pubs.rsc.org
As a well-known traditional Chinese medicine and functional food, Schisandra chinensis (S.
chinensis) has been proved to possess excellent neuroprotective effects, and particularly the …

Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer's disease

SS Lavekar, J Harkin, M Hernandez, C Gomes… - Scientific Reports, 2023 - nature.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of Aβ plaques and neurofibrillary tangles, resulting in synaptic loss and …

Cerebral hypoxia: its role in age-related chronic and acute cognitive dysfunction

B Snyder, SM Simone, T Giovannetti… - Anesthesia & …, 2021 - journals.lww.com
Postoperative cognitive dysfunction (POCD) has been reported with widely varying
frequency but appears to be strongly associated with aging. Outside of the surgical arena …

Dissociating effects of aging and genetic risk of sporadic Alzheimer's disease on path integration

L Colmant, A Bierbrauer, Y Bellaali, L Kunz… - Neurobiology of …, 2023 - Elsevier
Path integration is a spatial navigation ability that requires the integration of information
derived from self-motion cues and stable landmarks, when available, to return to a previous …

Assessing causal relationship between circulating cytokines and age-related neurodegenerative diseases: a bidirectional two-sample Mendelian randomization …

Z Yin, J Chen, M Xia, X Zhang, Y Li, Z Chen, Q Bao… - Scientific Reports, 2023 - nature.com
Numerous studies have reported that circulating cytokines (CCs) are linked to age-related
neurodegenerative diseases (ANDDs); however, there is a lack of systematic investigation …

Berberine Rescues D-Ribose-Induced Alzheimer's Pathology via Promoting Mitophagy

C Wang, Q Zou, Y Pu, Z Cai, Y Tang - International Journal of Molecular …, 2023 - mdpi.com
Mitochondrial dysfunction is considered an early event of Alzheimer disease (AD). D-ribose
is a natural monosaccharide that exists in cells, especially in mitochondria, and can lead to …

Lower mortality risk in APOE4 carriers with normal cognitive ageing

E Pirraglia, L Glodzik, Y Shao - Scientific Reports, 2023 - nature.com
Abnormal cognitive ageing, including dementia, poses serious challenges to health and
social systems in ageing populations. As such, characterizing factors associated with …

Federated Domain Adaptation via Transformer for Multi-site Alzheimer's Disease Diagnosis

B Lei, Y Zhu, E Liang, P Yang, S Chen… - … on Medical Imaging, 2023 - ieeexplore.ieee.org
In multi-site studies of Alzheimer's disease (AD), the difference of data in multi-site datasets
leads to the degraded performance of models in the target sites. The traditional domain …

Multi-dimensional deep learning drives efficient discovery of novel neuroprotective peptides from walnut protein isolates

L Lin, C Li, L Zhang, Y Zhang, L Gao, T Li, L Jin… - Food & Function, 2023 - pubs.rsc.org
Neurodegenerative diseases, such as Alzheimer's and Parkinson's, are multi-factor induced
neurological disorders that require management from multiple pathologies. The peptides …