Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … Reviews Molecular Cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Oxidative stress and regeneration

M Jaganjac, L Milkovic, N Zarkovic… - Free Radical Biology and …, 2022 - Elsevier
Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

[HTML][HTML] Reactive oxygen species and NRF2 signaling, friends or foes in cancer?

R Wang, L Liang, M Matsumoto, K Iwata, A Umemura… - Biomolecules, 2023 - mdpi.com
The imbalance between reactive oxygen species (ROS) production and clearance causes
oxidative stress and ROS, which play a central role in regulating cell and tissue physiology …

[HTML][HTML] Mitochondrial dysfunction: the hidden player in the pathogenesis of atherosclerosis?

G Ciccarelli, S Conte, G Cimmino, P Maiorano… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a multifactorial inflammatory pathology that involves metabolic processes.
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …

[HTML][HTML] Polyphenols as antioxidants for extending food shelf-life and in the prevention of health diseases: encapsulation and interfacial phenomena

M Costa, Z Sezgin-Bayindir, S Losada-Barreiro… - Biomedicines, 2021 - mdpi.com
Toxicity caused by the exposure to human-made chemicals and environmental conditions
has become a major health concern because they may significantly increase the formation …

[HTML][HTML] Activators of Nrf2 to counteract neurodegenerative diseases

R Amoroso, C Maccallini, I Bellezza - Antioxidants, 2023 - mdpi.com
Neurodegenerative diseases are incurable and debilitating conditions that result in
progressive degeneration and loss of nerve cells. Oxidative stress has been proposed as …

[HTML][HTML] The potential role of curcumin in modulating the master antioxidant pathway in diabetic hypoxia-induced complications

S Ghareghomi, M Rahban, Z Moosavi-Movahedi… - Molecules, 2021 - mdpi.com
Oxidative stress is the leading player in the onset and development of various diseases. The
Keap1-Nrf2 pathway is a pivotal antioxidant system that preserves the cells' redox balance. It …

[HTML][HTML] The effect of iron therapy on oxidative stress and intestinal microbiota in inflammatory bowel diseases: A review on the conundrum

R Loveikyte, AR Bourgonje, H van Goor, G Dijkstra… - Redox Biology, 2023 - Elsevier
One in five patients with Inflammatory Bowel Disease (IBD) suffers from anemia, most
frequently caused by iron deficiency. Anemia and iron deficiency are associated with worse …

[HTML][HTML] Polyploidy and myc proto-oncogenes promote stress adaptation via epigenetic plasticity and gene regulatory network rewiring

OV Anatskaya, AE Vinogradov - International Journal of Molecular …, 2022 - mdpi.com
Polyploid cells demonstrate biological plasticity and stress adaptation in evolution;
development; and pathologies, including cardiovascular diseases, neurodegeneration, and …

[HTML][HTML] Chronic exposure to the star polycation (SPc) nanocarrier in the larval stage adversely impairs life history traits in Drosophila melanogaster

S Yan, N Li, Y Guo, Y Chen, C Ji, M Yin, J Shen… - Journal of …, 2022 - Springer
Background Nanomaterials are widely used as pesticide adjuvants to increase pesticide
efficiency and minimize environmental pollution. But it is increasingly recognized that …