[HTML][HTML] In vitro and in vivo biological activities of azulene derivatives with potential applications in medicine

P Bakun, B Czarczynska-Goslinska, T Goslinski… - Medicinal Chemistry …, 2021 - Springer
Azulene is an aromatic hydrocarbon that possesses a unique chemical structure and
interesting biological properties. Azulene derivatives, including guaiazulene or …

Carbamazepine derivatives with P2X4 receptor-blocking activity

M Tian, A Abdelrahman, S Weinhausen, S Hinz… - Bioorganic & medicinal …, 2014 - Elsevier
Antagonists for the P2 receptor subtype P2X4, an ATP-activated cation channel receptor,
have potential as novel drugs for the treatment of neuropathic pain and other inflammatory …

Palladium-Catalyzed Q-Tube-Assisted Protocol for Synthesizing Diaza-dibenzo[a,e]azulene and Diaza-benzo[a]fluorene Derivatives via O2 Acid-Promoted Cross …

HM Ibrahim, H Behbehani - The Journal of Organic Chemistry, 2020 - ACS Publications
An appropriate and efficient Q-tube-assisted palladium-catalyzed strategy for the synthesis
of novel, unparalleled diaza-dibenzo [a, e] azulene and diaza-benzo [a] fluorene derivatives …

Synthesis of N-substituted dibenzoazepine–pyridazine derivatives as potential neurologically active drugs

M Erdoğan, A Daştan - Synthetic Communications, 2020 - Taylor & Francis
Syntheses of pyridazine derivatives of dibenzoazepine, starting from N-substituted-
dibenzoazepines, are reported here for the first time. In the reaction sequence, N-substitute …

Synthesis of Dibenzo[b,f]azepines via Palladium‐Catalyzed Cascade [4 + 3] Annulation of o‐Alkenyl Bromoarenes and o‐Bromoaniline Derivatives

XC Zhan, GQ Lin, JG Fu, XM Ji… - … Synthesis & Catalysis, 2023 - Wiley Online Library
Abstract A cascade [4+ 3] annulation of o‐alkenyl bromoarenes and o‐bromoaniline
derivatives was described. Various dibenzo [b, f] azepines with substitutions on the 10/11 …

[HTML][HTML] Effect of intermittency factor on singlet oxygen and PGE2 formation in azulene-mediated photodynamic therapy: A preliminary study

T Damrongrungruang, S Phiphitaporn… - … and Biophysics Reports, 2022 - Elsevier
In photodynamic therapy, intermittent irradiation modes that incorporate an interval between
pulses are believed to decrease the effect of hypoxia by permitting an interval of re …

New pyrazole derivatives and investigate their toxic effect in Hella and RD cancer cells lines

LS Abd, SM Salman, AH Alwan… - Research Journal of …, 2020 - indianjournals.com
New pyrazole derivatives have been synthesized by reaction of 2-(5-methoxy-3, 3-dimethyl-
1, 3-dihydro-indol-2ylidene)-malonaldehyde with substituted phenyl hydrazine …