[HTML][HTML] Inflammation and cancer
M Murata - Environmental health and preventive medicine, 2018 - Springer
Infection and inflammation account for approximately 25% of cancer-causing factors.
Inflammation-related cancers are characterized by mutagenic DNA lesions, such as 8-oxo-7 …
Inflammation-related cancers are characterized by mutagenic DNA lesions, such as 8-oxo-7 …
[HTML][HTML] Epigenetic alterations in cancer
Genetic and epigenetic modifications in DNA contribute to altered gene expression in aging
and cancer. In human cancers, epigenetic changes such as DNA methylation, histone …
and cancer. In human cancers, epigenetic changes such as DNA methylation, histone …
[HTML][HTML] Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data
DNA base modifications, such as C5-methylcytosine (5mC) and N6-methyldeoxyadenosine
(6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and …
(6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and …
Promoter DNA hypermethylation and paradoxical gene activation
DNA methylation is a stable epigenetic modification that contributes to the spatiotemporal
regulation of gene expression. The manner in which DNA methylation contributes to …
regulation of gene expression. The manner in which DNA methylation contributes to …
[HTML][HTML] Machine learning and deep learning methods that use omics data for metastasis prediction
Knowing metastasis is the primary cause of cancer-related deaths, incentivized research
directed towards unraveling the complex cellular processes that drive the metastasis …
directed towards unraveling the complex cellular processes that drive the metastasis …
[HTML][HTML] Epigenetic mechanisms and the hallmarks of cancer: An intimate affair
N Darwiche - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
Epigenetic mechanisms comprising DNA methylation, histone modifications, and noncoding
RNAs affect chromatin structure and regulate gene expression. These mechanisms control …
RNAs affect chromatin structure and regulate gene expression. These mechanisms control …
[HTML][HTML] Biology and pathogenesis of human osteosarcoma
JWV de Azevedo, TAAM Fernandes… - Oncology …, 2020 - spandidos-publications.com
Osteosarcoma (OS) is a bone tumor of mesenchymal origin, most frequently occurring
during the rapid growth phase of long bones, and usually located in the epiphyseal growth …
during the rapid growth phase of long bones, and usually located in the epiphyseal growth …
[HTML][HTML] Non-coding RNAs as mediators of epigenetic changes in malignancies
S Kumar, EA Gonzalez, P Rameshwar, JP Etchegaray - Cancers, 2020 - mdpi.com
Simple Summary This review discusses the role of non-coding RNAs (ncRNAs) in cancer
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …
[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation
DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
[HTML][HTML] Cell-free DNA approaches for cancer early detection and interception
JE Medina, NC Dracopoli, PB Bach, A Lau… - … for immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Rapid advancements in the area of early cancer detection have brought us closer to
achieving the goals of finding cancer early enough to treat or cure it, while avoiding harms of …
achieving the goals of finding cancer early enough to treat or cure it, while avoiding harms of …