Ophidian envenomation strategies and the role of purines

SD Aird - Toxicon, 2002 - Elsevier
Snake envenomation employs three well integrated strategies: prey immobilization via
hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine …

Tachykinins and tachykinin receptors: structure and activity relationships

TA Almeida, J Rojo, PM Nieto, FM Pinto… - Current medicinal …, 2004 - ingentaconnect.com
In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide
number of peptides with neurotransmitter activity have been identified in the past few years …

Pituitary adenylate cyclase-activating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: Evidence for PKA-mediated expression of …

A Agarwal, LM Halvorson, G Legradi - Molecular Brain Research, 2005 - Elsevier
The physiologic response to stress is highly dependent on the activation of corticotropin-
releasing hormone (CRH) neurons by various neurotransmitters. A particularly rich …

Role of substance P in the cardiovascular system

E Mistrova, P Kruzliak, MC Dvorakova - Neuropeptides, 2016 - Elsevier
This article provides an overview of the structure and function of substance P signalling
system and its involvement in the cardiovascular regulation. Substance P is an …

Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice

RM Teixeira, ARS Santos, SJ Ribeiro, JB Calixto… - European journal of …, 1996 - Elsevier
This study assessed the effects of intracerebroventricular administration of selective agonists
and antagonists for tachykinin NK1 and NK2 receptors on performance of mice in the …

Autoradiographic distribution of tachykinin NK2 binding sites in the rat brain: comparison with NK1 and NK3 binding sites

M Saffroy, Y Torrens, J Glowinski, JC Beaujouan - Neuroscience, 2003 - Elsevier
The autoradiographic distribution of tachykinin NK2 binding sites was determined in the
adult rat brain using [125I] neurokinin A in the presence of either senktide (NK3 agonist) and …

The Role of Tachykinins and the Tachykinin NK1 Receptor in Nausea and Emesis

PLR Andrews, JA Rudd - Tachykinins, 2004 - Springer
Nausea and vomiting are both components of the body's defensive system to protect against
the effects of accidentally ingested toxins. Whilst these responses have survival value in the …

Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress

J Culman, S Klee, C Ohlendorf, T Unger - Journal of Pharmacology and …, 1997 - ASPET
The neurokinins, substance P (SP) and neurokinin A (NKA) represent natural, nonspecific
ligands of NK1 and NK2receptors. In our study in conscious rats, we tested the hypothesis …

A 25 year adventure in the field of tachykinins

JC Beaujouan, Y Torrens, M Saffroy, ML Kemel… - Peptides, 2004 - Elsevier
Several aspects of our 25 year adventure in the field of tachykinins will be successively
described. They concern: substance P (SP) synthesis and release in the basal ganglia, the …

Combinations of neurokinin receptor antagonists reduce visceral hyperalgesia

EH Kamp, DR Beck, GF Gebhart - Journal of Pharmacology and …, 2001 - ASPET
The effect of selective neurokinin receptor (NKR) antagonists for the NK1R (SR140, 333),
NK2R (SR48, 968), and NK3R (SR142, 801) on the visceromotor response to noxious …