Simple Summary Prophylactic interventions are critical for BRCA1/2 mutation carriers to
reduce the risks of hereditary breast and ovarian cancer (HBOC). This systematic review and …

Background: Primary prevention and early detection of hereditary breast cancer has been
one of the main topics of breast cancer research in recent decades. The knowledge of risk …

With widespread testing for susceptibility genes, increasing numbers of women are being
identified to carry a mutation in one of many genes which renders them susceptible to …

There is evidence suggesting that endocrine interventions such as hormone replacement
therapy and hormonal contraception can increase breast cancer (BC) risk. Sexual steroid …

Background High-risk lesions (HRL) of the breast are risk factors for future breast cancer
development and may be associated with a concurrent underlying malignancy when …

For several decades, researchers have sought to divide breast cancer patients into
meaningful subgroups with the intention of refining treatment strategies–to find the right drug …

Breast cancer is a prevalent disease that primarily affects women globally, but it can also
affect men. Early detection is crucial for better treatment outcomes and mammography is a …

Background This study investigated the multifaceted role of BRCA2 (breast cancer 2) in
various cancer types, with a specific focus on thyroid carcinoma (THCA). Methods Data sets …

Background: Hereditary breast and ovarian cancers (HBOCs) pose significant health risks
worldwide and are mitigated by prophylactic interventions. However, a meta-analysis of their …