[HTML][HTML] The plasticity of pancreatic cancer stem cells: Implications in therapeutic resistance
The ever-growing perception of cancer stem cells (CSCs) as a plastic state rather than a
hardwired defined entity has evolved our understanding of the functional and biological …
hardwired defined entity has evolved our understanding of the functional and biological …
Bioactive components and molecular mechanisms of Salvia miltiorrhiza Bunge in promoting blood circulation to remove blood stasis
B Wei, C Sun, H Wan, Q Shou, B Han, M Sheng… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge (SM) is an outstanding
herbal medicine with various traditional effects, especially promoting blood circulation to …
herbal medicine with various traditional effects, especially promoting blood circulation to …
[HTML][HTML] Tanshinone IIA protects human coronary artery endothelial cells from ferroptosis by activating the NRF2 pathway
L He, YY Liu, K Wang, C Li, W Zhang, ZZ Li… - Biochemical and …, 2021 - Elsevier
The pathogenesis of atherosclerosis is closely related to endothelial cell injury caused by
lipid peroxidation-induced ferroptosis. Tanshinone IIA (TSA) protects endothelial tissues …
lipid peroxidation-induced ferroptosis. Tanshinone IIA (TSA) protects endothelial tissues …
Single‐Cell RNA Sequencing Reveals the Temporal Diversity and Dynamics of Cardiac Immunity after Myocardial Infarction
Myocardial infarction (MI) is strongly associated with the temporal regulation of cardiac
immunity. However, a variety of current clinical trials have failed because of the lack of post …
immunity. However, a variety of current clinical trials have failed because of the lack of post …
Tanshinone IIA ameliorates experimental diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress in cardiomyocytes via SIRT1
S Wu, D Lu, B Gajendran, Q Hu, J Zhang… - Phytotherapy …, 2023 - Wiley Online Library
Diabetic cardiomyopathy (DCM) is a common complication in patients with diabetes, and
ultimately leads to heart failure. Endoplasmic reticulum stress (ERS) induced by abnormal …
ultimately leads to heart failure. Endoplasmic reticulum stress (ERS) induced by abnormal …
Nanomedicine-based immunotherapy for Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease caused by the
deposition of amyloid β (Aβ) fibrils forming extracellular plaques and the development of …
deposition of amyloid β (Aβ) fibrils forming extracellular plaques and the development of …
[HTML][HTML] Multifaceted pharmacological potentials of curcumin, genistein, and tanshinone IIA through proteomic approaches: an in-depth review
Simple Summary Over the years, alternative and complementary medicine have garnered
much attention all across the globe. To this end, phytochemicals have intriguing potential …
much attention all across the globe. To this end, phytochemicals have intriguing potential …
Biosynthesis and Regulatory Mechanisms of Bioactive Compounds in Salvia miltiorrhiza, a Model System for Medicinal Plant Biology
S Lu - Critical Reviews in Plant Sciences, 2021 - Taylor & Francis
Salvia miltiorrhiza is one of the most well known species in the genus Salvia of the
Lamiaceae with great economic, academic and medicinal value. It was recorded as a …
Lamiaceae with great economic, academic and medicinal value. It was recorded as a …
Tanshinone-IIA mediated neuroprotection by modulating neuronal pathways
K Sherawat, S Mehan - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
The progression of neurological diseases is mainly attributed to oxidative stress, apoptosis,
inflammation, and trauma, making them a primary public concern. Since no drugs can stop …
inflammation, and trauma, making them a primary public concern. Since no drugs can stop …
[HTML][HTML] Tanshinone-I for the treatment of uterine fibroids: Molecular docking, simulation, and density functional theory investigations
Uterine fibroids (UF), most prevalent gynecological disorder, require surgery when
symptomatic. It is estimated that between 25 and 35 percent of women wait until the …
symptomatic. It is estimated that between 25 and 35 percent of women wait until the …