Background Neurological disorders, such as ischemic stroke, spinal cord injury,
neurodegenerative diseases, and glioblastoma often lead to long-term disability and death …

Heart disease is one of the principal death reasons around the world and there is a growing
requirement to discover novel healing targets that have the potential to avert or manage …

Tanshinone IIA (TanIIA) and gene therapy both hold promising potentials in hepatocellular
carcinoma (HCC) treatment. However, low solubility and poor bioavailability of TanIIA limit …

(1) Background: Osteoarthritis (OA) is a crippling condition characterized by chondrocyte
dedifferentiation, cartilage degradation, and subsequent cartilage defects. Unfortunately …

Head and neck squamous cell carcinoma (HNSCC) is a worldwide public health problem; its
incidence is increasing and it is now the sixth most common cancer type worldwide. As …

Fourteen previously undescribed diterpenoids, including seven ent-pimarane-type
diterpenoids and seven phytane-type diterpenes, together with five known ones, were …

Background Many studies have confirmed the association of aquaporins (AQPs) with
abnormal amniotic fluid volume (AFV). In our previous experiments, we found that …

Colorectal cancer (CRC) is one of the most significant forms of human cancer. It is
characterized by its heterogeneity because several molecular factors are involved in …

Background Lung cancer is the most prevalent of all cancers, causing the highest number of
cancer-related deaths in men and the second-highest number in women worldwide. Recent …

Heat stress can cause testicular damage and affect male fertility. Tanshinone IIA (TSA) is a
monomer substance derived from plants, with antioxidant and anti-apoptotic effects. Whether …