Tanshinone IIA alleviates bleomycin-induced pulmonary fibrosis by inhibiting Zbtb16

H Zhang, J Qiu, Q Zhao, Y Zhang, H Zheng… - Pulmonary …, 2024 - Elsevier
Pulmonary fibrosis is a complex disease that can occur in a variety of clinical settings. The
Zinc Finger and BTB Domain Containing 16 (Zbtb16) is a transcription factor and has not …

Reassessing the molecular structures of some previously isolated abietane diterpenoids with a naphthalene moiety and the structure-activity relationship (SAR) of …

Z Nazemosadat-Arsanjani, M Moein, S Yousuf, O Firuzi… - Phytochemistry, 2022 - Elsevier
Crystals of previously described para-naphthoquinone abietane diterpenoids 12, 16-
dideoxy-aegyptinone B and 12-deoxy-salvipisone were obtained from Zhumeria majdae …

Tanshinone IIA suppresses ferroptosis to attenuate renal podocyte injury in diabetic nephropathy through the embryonic lethal abnormal visual‐like protein 1 and acyl …

S Zhu, Z Kang, F Zhang - Journal of Diabetes Investigation, 2024 - Wiley Online Library
Abstract Aims/Introduction Tanshinone IIA (TIIA) is one of the main components of the root of
the red‐rooted Salvia miltiorrhiza Bunge. However, the molecular mechanisms underlying …

Tanshinone IIA enhances the ovarian reserve and attenuates ovarian oxidative stress in aged mice

L Bai, G He, C Gao, H Yang, M Li… - Veterinary Medicine …, 2022 - Wiley Online Library
Abstract Background Tanshinone IIA (TSA), a major lipophilic component extracted from the
roots of Salvia miltiorrhiza Bunge, has been widely used in China for its various biological …

Role of viruses in nanoparticles synthesis

C Srinivasa, GC Kavitha, M Pallavi… - … : green synthesis and …, 2021 - Springer
Nanotechnology has revolutionized with lots of applications in the medicinal field to prevent,
detect and treat several biological problems including disease and infections. The plant …

[HTML][HTML] Prospective Pharmacological Potential of Cryptotanshinone in Cancer Therapy

A Ahamed, M Hasan, A Samanta, SSM Alam… - Pharmacological …, 2023 - Elsevier
ABSTRACT Background: Cryptotanshinone (CPT), a Traditional Chinese Medicine (TCM)
has recently gained remarkable interest as a potent alternative cancer therapeutic. The sole …

[HTML][HTML] Tanshinone IIA protects motor neuron-like NSC-34 cells against lipopolysaccharide-induced cell injury by the regulation of the lncRNA TCTN2/miR-125a-5p …

Q Yan, Y Xun, D Lei, H Zhai - Regenerative Therapy, 2023 - Elsevier
Abstract Background Tanshinone IIA (TSIIA) exerts a protective role in spinal cord injury
(SCI). However, the mechanism of TSIIA activity in SCI remains to be elucidated. Methods …

Cosmetic and medical applications of microbial nanotechnology

EA Bhat, N Sajjad, I Rather - Microbial Nanotechnology: Green Synthesis …, 2021 - Springer
Nanotechnology demonstrates success in the research and development arena by
emerging product production by providing creative solutions and a promising and …

[HTML][HTML] Tanshinone IIA and Cryptotanshinone Counteract Inflammation by Regulating Gene and miRNA Expression in Human SGBS Adipocytes

S Carpi, S Quarta, S Doccini, A Saviano, N Marigliano… - Biomolecules, 2023 - mdpi.com
Inflammation of the adipose tissue contributes to the onset and progression of several
chronic obesity-related diseases. The two most important lipophilic diterpenoid compounds …

[HTML][HTML] Protective effects of tanshinone ⅡA on sepsis-induced multiple organ dysfunction: a literature review

W Lili, F Ju, Z Daqian, W Junshuai… - Journal of Traditional …, 2023 - ncbi.nlm.nih.gov
Abstract TanshinoneⅡA (TanⅡA) is a noteworthy lipophilic diterpene compound derived
from the dried roots of the Traditional Chinese Medicine Danshen (Radix Salviae …