NPs loaded with zoledronic acid as an advanced tool for cancer therapy

S Fathi-karkan, M Zeeshan, M Qindeel… - Journal of Drug Delivery …, 2023 - Elsevier
Zoledronic acid (ZA) has been shown to be beneficial against cancer both directly and
indirectly. However, because of its fast absorption by bone, its use in extraskeletal …

Onion-like doxorubicin-carrying polymeric nanomicelles with tumor acidity-sensitive dePEGylation to expose positively-charged chitosan shell for enhanced cancer …

SY Huang, NT Yeh, TH Wang, TC Hsu, HY Chin… - International Journal of …, 2023 - Elsevier
To effectively promote antitumor potency of doxorubicin (DOX), a regularly used
chemotherapy drug, the tumor acidity-responsive polymeric nanomicelles from self …

Tumor-activated targetable photothermal chemotherapy using IR780/zoledronic acid-containing hybrid polymeric nanoassemblies with folate modification to treat …

YL Liu, TH Wang, NT Yeh, WJ Huang, BS Tzang, IT Wu… - Nanoscale, 2024 - pubs.rsc.org
To effectively treat aggressive breast cancer by tumor-activated targetable photothermal
chemotherapy, in this work, folate (FA)-modified hybrid polymeric nanoassemblies (HPNs) …

Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity

J Shi, B Ma, Y Zhang, H Yong, Z Li, X Huang… - Chemistry of …, 2023 - ACS Publications
Cancer therapy is a global biomedical challenge, and a number of promising anticancer
therapeutics, such as small-molecule drugs, proteins, nucleic acids, photothermal agents …

pH-triggered “PEG” sheddable and folic acid-targeted nanoparticles for docetaxel delivery in breast cancer treatment

F Sui, Z Fang, L Li, X Wan, Y Zhang, X Cai - International Journal of …, 2023 - Elsevier
Multifunctional nanoparticles have attracted significant attentions for oncology and cancer
treatment. In fact, they could address critical point for tumour treatment by creating a stimuli …

One-pot preparation of pH-and redox-responsive polymeric microgel as an efficient carrier for improved breast cancer therapy

D Huang, J Zhu, MF Xu, J Chen, X Gao, L Zhao… - Colloids and Surfaces A …, 2024 - Elsevier
Nano-drug carriers responsive to external stimuli have attracted greater scientific attention
for the treatment of cancer. In this study, biodegradable DPA-DSDMA-PEG microgels were …

Acidity/hydrogen peroxide-responsive PEGylated chitosan-modified polydopamine nanoparticles to realize effective photothermal conversion and intracellular drug …

MY Shen, YH Chen, NT Yeh, TH Wang… - European Polymer …, 2023 - Elsevier
To realize effective photothermal conversion and intracellular drug delivery for application of
cancer treatment, an acidity/hydrogen peroxide-responsive nanoparticle system comprising …

Unraveling the Role of miR-200b-3p in Attention-Deficit/Hyperactivity Disorder (ADHD) and Its Therapeutic Potential in Spontaneously Hypertensive Rats (SHR)

TM Chang, HL Lin, CC Tzang, JA Liang, TC Hsu… - Biomedicines, 2024 - mdpi.com
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
in children with unknown etiology. Impaired learning ability was commonly reported in …

Ultrasound-mediated PLGA-PEI Nanobubbles Carrying STAT6 SiRNA Enhances NSCLC Treatment via Repolarizing Tumor-associated Macrophages from M2 to M1 …

H Shu, W Lv, Z Ren, H Li, T Dong… - Current Drug …, 2024 - ingentaconnect.com
Background: Tumor-associated macrophages (TAMs) are crucial for non-small cell lung
cancer (NSCLC) development. Objective: In this study, polylactic acid-co-glycolic acid …