Aim: Timing of radium-223 (Ra-223) in metastatic castration-resistant prostate cancer
(mCRPC) remains challenging due to alternative options and short window of opportunity …

Background Prostate cancer (PC) is the most frequently diagnosed cancer in North
American men. Pathologists are in critical need of accurate biomarkers to characterize PC …

Metastatic burden is a critical factor for therapy decision‐making in metastatic hormone‐
sensitive prostate cancer. The present study aimed to identify prognostic factors in men with …

Morning-preference chronotype has been found to be protective against breast and prostate
cancer. Sex hormones have been implicated in relation to chronotype and the development …

Bone tissues are the main metastatic sites of many cancers, and bone metastasis is an
important cause of death. When bone metastasis occurs, dynamic interactions between …

Increasing evidence reveals that the interaction between tumor cells and tumor-associated
macrophages (TAMs) facilitates the progression of prostate cancer, but the related …

We report herein the design, synthesis, and pharmacological characterization of a library of
novel aryl pyrazol-1-yl-propanamides as selective androgen receptor degraders (SARDs) …

Increasing evidence demonstrated that noncoding RNAs (lncRNA, miRNA) play important
roles in the cancer development. LncRNA NEAT1 functions as an oncogene in many …

Abstract Background and Aims: Prostate specific membrane antigen (PSMA) is specifically
expressed on prostate epithelial cells and markedly overexpressed in almost all prostate …

Adipocyte–tumor cell cross-talk is one of the critical mediators of tumor progression and an
emerging facilitator of therapy evasion. Tumor cells that metastasize to adipocyte-rich bone …