Viral hepatitis, secondary to infection with hepatitis A, B, C, D, and E viruses, are a major
public health problem and an important cause of morbidity and mortality. Despite the huge …

Natural killer (NK) cells are pivotal effectors of the innate immunity protecting an individual
from microbes. They are the first line of defense against invading viruses, given their …

Hepatitis C virus (HCV) remains a global public health problem even though more than 95%
of infections can be cured by treatment with direct-acting antiviral agents. Resolution of …

Viral hepatitis is one of the main causes leading to hepatocellular carcinoma (HCC). The
continued rise in incidence of HCC suggests additional factors following infection may be …

Tuberculosis (TB) is a leading global public health problem; however, the mechanisms
underlying the immunopathology of TB progression are not well understood. It is currently …

Some NK cell subpopulations may be involved in the modulation of fibrogenesis in the liver.
The aim of the study was to evaluate the relationship between the number and phenotype of …

Direct-acting antiviral agents (DAAs) that allow for rapid clearance of hepatitis C virus (HCV)
may evoke immunological changes. Some cases of rapid de novo hepatocellular carcinoma …

Natural Killer (NK) cells are key effectors of the innate immune system which represent the
first line of defense against viral infections. NK cell activation depends on the engagement of …

Background One of the prominent causes of chronic liver disease worldwide is the hepatitis
C virus (HCV). HCV believed that innate immunity contributes to a sustained virological …

Multiple immune cells and their products in the liver together form a complex and unique
immune microenvironment, and preclinical models have demonstrated the importance of …