Transplantation of bone marrow mesenchymal stem cells improves cognitive deficits and alleviates neuropathology in animal models of Alzheimer's disease: a meta …

C Qin, Y Lu, K Wang, L Bai, G Shi, Y Huang… - Translational …, 2020 - Springer
Background Alzheimer's disease is a neurodegenerative disorder. Therapeutically, a
transplantation of bone marrow mesenchymal stem cells (BMMSCs) can play a beneficial …

Human Placenta-Derived Mesenchymal Stem Cells Promote Hepatic Regeneration in CCl4-Injured Rat Liver Model via Increased Autophagic Mechanism

J Jung, JH Choi, Y Lee, JW Park, IH Oh, SG Hwang… - Stem …, 2013 - academic.oup.com
Mesenchymal stem cells (MSCs) have great potential for cell therapy in regenerative
medicine, including liver disease. Even though ongoing research is dedicated to the goal of …

Functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer's disease: inhibition of neuroinflammation

C Qin, Y Li, K Wang - Journal of inflammation research, 2021 - Taylor & Francis
The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …

Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair

M Li, JS Hale, JN Rich, RM Ransohoff, JD Lathia - Trends in neurosciences, 2012 - cell.com
The dynamic relation between stem cells and their niche governs self-renewal and
progenitor cell deployment. The chemokine CXCL12 (CXC motif ligand 12) and its signaling …

RETRACTED: Potential of bone marrow mesenchymal stem cells in management of Alzheimer's disease in female rats

AM Salem, HH Ahmed, HM Atta… - Cell biology …, 2014 - Wiley Online Library
Alzheimer's disease (AD) has been called the disease of the century with significant clinical
and socioeconomic impacts. Pharmacological treatment has limited efficacy and only …

Intravenously injected mesenchymal stem cells penetrate the brain and treat inflammation-induced brain damage and memory impairment in mice

O Lykhmus, L Koval, L Voytenko, K Uspenska… - Frontiers in …, 2019 - frontiersin.org
Neuroinflammation is regarded as one of the pathogenic factors of Alzheimer disease (AD).
Previously, we showed that mice regularly injected with bacterial lipopolysaccharide (LPS) …

[HTML][HTML] Stem cell therapies in Alzheimer's disease: applications for disease modeling

Z Si, X Wang - Journal of Pharmacology and Experimental …, 2021 - ASPET
Alzheimer's disease (AD) is a neurodegenerative disease with complex pathologic and
biologic characteristics. Extracellular β-amyloid deposits, such as senile plaques, and …

Human bone marrow-derived mesenchymal stem cell applications in neurodegenerative disease treatment and integrated omics analysis for successful stem cell …

SG Kim, NP George, JS Hwang, S Park, MO Kim… - Bioengineering, 2023 - mdpi.com
Neurodegenerative diseases (NDDs), which are chronic and progressive diseases, are a
growing health concern. Among the therapeutic methods, stem-cell-based therapy is an …

Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury

F Yin, L Guo, C Meng, Y Liu, R Lu, P Li, Y Zhou - Brain research, 2014 - Elsevier
It is unknown whether transplantation of bone marrow mesenchymal stem cells (BM-MSCs)
can repair spinal cord ischemia-reperfusion injury (SCII) in a rat model through an anti …

Toll-like receptor 4, osteoblasts and leukemogenesis; the lesson from acute myeloid leukemia

Ø Bruserud, H Reikvam, AK Brenner - Molecules, 2022 - mdpi.com
Toll-like receptor 4 (TLR4) is a pattern-recognizing receptor that can bind exogenous and
endogenous ligands. It is expressed by acute myeloid leukemia (AML) cells, several bone …