Chimeric antigen receptor T (CAR-T) cell therapy is a promising and precise targeted
therapy for cancer that has demonstrated notable potential in clinical applications. However …

Colorectal cancer (CRC) is the third most common cancer globally and presents a significant
challenge owing to its high mortality rate and the limitations of traditional treatment options …

Chimeric antigen receptor (CAR) T cell therapy has become the standard of care for multiple
hematological malignancies. In contrast, treatment success in solid tumors with CAR T cells …

The epithelial cell adhesion molecule (EpCAM) is a single transmembrane protein on the
cell surface. Given its strong expression on epithelial cells and epithelial cell-derived tumors …

Objective To evaluate the safety and preliminary efficacy of IMC001, an epithelial cell
adhesion molecule (EpCAM)-targeted CAR-T cell therapy, in patients with advanced gastric …

Chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising treatment
option for various types of cancers. Although it has shown remarkable effectiveness, this …

The myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal
disorders caused by somatic driver mutations affecting the hematopoietic stem and …