The roles of the amyloid beta monomers in physiological and pathological conditions

TG Schreiner, OD Schreiner, M Adam, BO Popescu - Biomedicines, 2023 - mdpi.com
Amyloid beta peptide is an important biomarker in Alzheimer's disease, with the
amyloidogenic hypothesis as one of the central hypotheses trying to explain this type of …

[HTML][HTML] Lynx1 and the family of endogenous mammalian neurotoxin-like proteins and their roles in modulating nAChR function

TB Palumbo, JM Miwa - Pharmacological Research, 2023 - Elsevier
The promise of nicotinic receptors as a therapeutic target has yet to be fully realized, despite
solid data supporting their involvement in neurological and neuropsychiatric diseases. The …

GLP-1/Sigma/RAGE Receptors: An evolving picture of Alzheimer's Disease pathology and treatment

Z Wali, SH Hattiwale, A Jamal, S Parvez - Ageing Research Reviews, 2023 - Elsevier
According to the facts and figures 2023 on Alzheimer's disease (AD) stated that 6.7 million
Americans over the age of 65 have AD. The scenario of AD has reached up to the maximum …

Role of Alpha-7-nicotinic acetylcholine receptor in Alzheimer's disease

S Singh, N Agrawal, A Goyal - CNS & Neurological Disorders …, 2024 - ingentaconnect.com
Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions worldwide. One
of the leading hypotheses for the underlying cause of AD is a reduction in nicotinic receptor …

[HTML][HTML] Alzheimer's disease is an inherent, natural part of human brain aging: An integrated perspective

I Ferrer - Free Neuropathology, 2022 - ncbi.nlm.nih.gov
Alzheimer disease is one of the most challenging demons in our society due to its very high
prevalence and its clinical manifestations which cause deterioration of cognition …

Generation of a helper phage for the fluorescent detection of peptide-target interactions by dual-display phages

LM De Plano, S Oddo, SPP Guglielmino, A Caccamo… - Scientific Reports, 2023 - nature.com
Phage display is a molecular biology technique that allows the presentation of foreign
peptides on the surface of bacteriophages. It is widely utilized for applications such as the …

Next generation cognition-aware hearing aid devices with microwave sensors: Opportunities and challenges

U Anwar, T Arslan, A Hussain, P Lomax - IEEE Access, 2022 - ieeexplore.ieee.org
The strong association between hearing loss and cognitive decline has developed into a
major health challenge that calls for early detection, diagnosis and prevention. Hearing loss …

[HTML][HTML] Donepezil beyond Alzheimer's disease? A narrative review of therapeutic potentials of donepezil in different diseases

P Pooladgar, M Sakhabakhsh, A Taghva… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Donepezil hydrochloride is an acetylcholine esterase inhibitor studied and approved to treat
Alzheimer's disease (AD). However, this drug can have positive therapeutic potential in …

Etiology, pathogenesis of Alzheimer's disease and amyloid beta hypothesis

SM Kamble, KR Patil, AB Upaganlawar - Alzheimer's Disease and …, 2024 - Elsevier
Alzheimer disease (AD) is advanced neurodegenerative condition characterized by
dementia, accounting for an estimated 60%–70% of cases worldwide. AD is progressive …

[HTML][HTML] The long non-coding RNA BDNF-AS induces neuronal cell apoptosis by targeting miR-125b-5p in Alzheimer's disease models

H Ren, W Qiu, B Zhu, Q Li, C Peng… - Advances in Clinical …, 2024 - advances.umw.edu.pl
Background. At least 55 million individuals suffer from dementia globally, of which
Alzheimer's disease (AD) accounts for 60–70% of cases. Alzheimer's disease is the only …